Validation of a Portable Indirect Calorimeter

Human Energy Expenditure Clinical Trial

Official title: Validation of the Apollo EE Device, Indirect Calorimetry

Status Terminated

Clinical Trial Summary

This study plans to test the accuracy of a new device (the Apollo EE Device) that measures resting energy expenditure (REE) using only oxygen consumed (VO2). Findings from this study will help determine how this new device compares to the gold standard, indirect calorimetry, which measures REE using VO2 and carbon dioxide production (VCO2). Findings may help develop less expensive and more accessible means of measuring energy expenditure.

Clinical Trial Description

The gold standard for measuring resting metabolic rate (RMR) is metabolic carts that measure oxygen consumption (VO2) and carbon dioxide production (VCO2). The energy equivalent of VO2 ranges from ~4.7-5.0 kcals/L, depending on the ratio of carbohydrate, fat, and protein oxidized. However, RMR can be measured based solely on VO2, because VCO2 has a relatively small effect on energy expenditure estimation. A device that measures RMR based on VO2 and eliminates the need for measuring VCO2 could provide a simple and less expensive alternative to metabolic carts and may have important clinical applications. The overarching goal of this proposal is to validate such a metabolic system by comparing its ability to accurately measure RMR against a metabolic cart. ;

Related Conditions & MeSH terms

• Human Energy Expenditure

• NCT number: NCT04469452
• Study type: Observational
• Source: University of Colorado, Denver
• Status: Terminated
• Start date: September 1, 2020
• Completion date: November 28, 2023