Clinical Trials Logo

Clinical Trial Summary

Encephalitics is a serious condition in which the brain becomes inflamed (swollen). It usually happens as a direct result of virus, such as herpes simplex virus (HSV).

HSV encephalitis is often treated with the drug acyclovir (an antiviral drug which slows the growth and spread of HSV in the body). Despite this however, around 2 out of every 3 people will have memory difficulties long term. Dexamethasone is a corticosteroid medication, which works by preventing the release of natural chemicals in the body which cause inflammation. It is possible that dexamethasone could help to reduce in swelling of the brain may improve the recovery of patients with HSV encephalitis. The aim of this study is to find out whether treatment with dexamethasone can improve long-term health outcomes in adults with HSV Encephalitis.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03084783
Study type Interventional
Source University Hospital, Grenoble
Contact Jean-Paul STAHL, MD
Phone 04 76 76 68 13
Email jpstahl@chu-grenoble.fr
Status Recruiting
Phase Phase 3
Start date November 1, 2018
Completion date December 1, 2020

See also
  Status Clinical Trial Phase
Completed NCT05127395 - Impact of Obesity on Clinical Outcomes in Patients Receiving Acyclovir for HSV Encephalitis"