HPV-Related Carcinoma Clinical Trial
Official title:
Radiosensitivity of HPV-related Tumors: Towards a Genomic Approach - ICARUS Project
The purpose of this study is therefore to analyze the genomic profiles of prognosis and radiosensitivity of Human Papilloma Virus (HPV) related tumors from different body sites (oropharynx, uterine cervix, and anus), considering them as a unified entity regardless of the site of origin within the body.
The present study (ICARUS - genomIC RAdiosensitivity viRUS) involves the collection of data (retrospective and prospective) from an extensive cohort of patients with HPV-related tumors of the oropharynx, cervix, and anus. The aim is to: 1. investigate the role of Cl2 in non-oropharyngeal HPV-related tumors, and 2. compare the Radiation Sensitivity Index (RSI) values of HPV-related tumors in patients who responded to radiotherapy (responders) with those of patients with radioresistant tumors (non-responders). ;
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