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Ustekinumab for the Treatment of Giant Cell Arteritis — UGCA  

Giant Cell Arteritis Clinical Trial

Official title:
Open Label Study to Test the Safety and Efficacy of Ustekinumab in Patients With Giant Cell Arteritis

Clinical Trial Summary

The purpose of this study is to determine whether ustekinumab is effective in the treatment of Giant Cell Arteritis (GCA)

Clinical Trial Description

The objective of this study is to evaluate the efficacy and safety of ustekinumab, an interleukin (IL)-12/23 inhibitor, in patients with GCA

Hypothesis IL-12/23 pathway blockade may maintain disease remission in patients with GCA

Specific Aims

- To evaluate the safety and tolerability of ustekinumab administration in 20 patients with GCA

- To evaluate the efficacy of ustekinumab for remission maintenance and glucocorticoid sparing in 20 patients with GCA ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02955147
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date December 1, 2016
Completion date September 19, 2019
View Details
See also
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