Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration

Horizontal Ridge Deficiency Clinical Trial

— VIP-CT  

Official title:

Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration in Horizontal Ridge Augmentation in Aesthetic Zone

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05813340
• Other study ID #: 111111
• Status: Recruiting
• Phase: N/A
• Start date: January 1, 2023
• Est. completion date: December 1, 2023

Study information

• Verified date: April 2023
• Source: Cairo University
• Contact: Esraa Ismail, Masters
• Phone: 01155400246
• Email: esera.hady[@]dentistry.cu.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

this study compares 2 techniques in guided bone regeneration for horizontal ridge augmentation in aesthetic zone

Description:

Guided bone regeneration is a technique for ridge augmentation using membranes The membrane of GBR is an essential component of treatment as it has some important characteristics manageability, space-making ability, and adequate mechanical, physical properties, and biocompatibility Collagen membranes are the most commonly used and can inhibit soft tissue growth in bone defects and achieve better wound healing and bone regeneration. on the other hand, a Vascularized inter-positional periosteal connective tissue flap is a flap that has been used as a substitute for the collagen membrane with promising results. Vascularized inter-positional periosteal connective tissue flap (VIPCTF) may have many advantages over traditional collagen membranes such as; high vascularity, decreased cost (as it may substitute membrane), providing an increase in soft tissue thickness, and reusability. So Evaluation of effect of vascularized interpositional periosteal connective tissue flap on horizontal ridge augmentation grafting of the anterior maxilla in comaprison with the collagen membranes

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 24
• Est. completion date: December 1, 2023
• Est. primary completion date: June 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Patients with a horizontal defect in anterior and premolar areas of the maxilla (aesthetic zone).

Exclusion Criteria:

• poor oral hygiene
• radiation therapy of head and neck cancer
• intraoral soft and hard tissue lesions
• Heavy smoking
• Bone pathology

Related Conditions & MeSH terms

• Horizontal Ridge Deficiency

Intervention

Procedure:
• Vascularized inter-positional periosteal connective tissue flap
It is a vascularized pedicled flap derived from the hard palate that can be used as a barrier to prevent in growth of soft tissue in guided bone regeneration and to increase soft tissue quantity

Locations

Country	Name	City	State
Egypt	Faculty of dentistry Cairo university	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Khajehahmadi, S., & Rahpeyma, A. (2014). Vascularized interpositional periosteal connective tissue flap in implant dentistry. Journal of Dental Implants, 4(1), 29. https://doi.org/10.4103/0974-6781.130952

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Amount of bone width gain (horizontal augmentation)	bone width gain is measured in millimeters by Cone beam computed tomography	6 months
Secondary	Percentage of bone formation in the bone biopsy	Area percentage of newly formed bone is measured through histomorphometric analysis	6 months