Homocysteine Clinical Trial
Official title:
Study on the Effect of Compound Nutrients on Reducing Homocysteine -- A 3-month Double-blind Randomized Controlled Trial
The purpose of this study is to determine whether supplementation of compound nutrients, including folic acid, vitamin B6, vitamin B12, and betaine, will decrease the level of plasma homocysteine in Chinese adults with homocysteine levels above 10 μmol/L.
Status | Recruiting |
Enrollment | 220 |
Est. completion date | December 31, 2025 |
Est. primary completion date | December 31, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility | Inclusion Criteria: 1. Aged 18 - 65 years; 2. Concentration of plasma homocysteine is between 10 and 100 µmol/L; 3. Free from any supplements or drugs that may decrease plasma homocysteine concentration for at least 1 month prior to the beginning of study; 4. Willing to participate in the study and sign informed consent. Exclusion Criteria: 1. Pregnant or lactating women; 2. Allergic physique or allergic to our compound nutrients tablets; 3. Complicated with severe diseases; 4. Unable to conduct study procedures; 5. Participating in any other intervention studies. |
Country | Name | City | State |
---|---|---|---|
China | SunYat-sen University | Guangzhou | Guangdong |
Lead Sponsor | Collaborator |
---|---|
Sun Yat-sen University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | levels of homocysteine | At baseline, 4 weeks, and 12 weeks, blood samples will be drawn and levels of homocysteine will be determined in the two groups. | 12 weeks |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00172250 -
The Study of Relationship of Plasma Concentrations of Folic Acid, Vitamin B and Homocysteine With Carotid Atherosclerosis and Endothelium-Dependent Vasodilatation of Geriatric and Young Patients in the Ambulatory Care Department of NTUH
|
N/A | |
Completed |
NCT02575092 -
The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment
|
Phase 2/Phase 3 | |
Enrolling by invitation |
NCT03595163 -
Effects of Propofol and Sevoflurane on Blood Folic Acid and Homocysteine Concentrations in Children
|
N/A |