Multiple Myeloma Clinical Trial
Official title:
Single Nucleotide Polymorphism (SNP)-Based Prediction of Oral Mucositis Risk in Patients Receiving Hematopoietic Stem Cell Transplants
The goal of this study is to gain new knowledge about genetic risk factors thta may affect the development of mucositis, the chemotherapy-induced sores in the mouth and esophagus following HSCT. The study seeks to understand if different forms of genes result in an increased risk of sores in the mouth and esophagus.
Subjects will be provided with a saliva collection kit which can be used at home. Subjects
will return the collection kit in a paid, pre-addressed mailer to the laboratory at
Biomodels. The laboratory will isolate and store the DNA located in the cells of the saliva.
A portion of this DNA will be used to analyze the different forms of genes. The remainder of
the DNA will be destroyed when this study is completed. Biomodels will not be provided with
patient identifiers.
The investigators will also collect information from medical records, including information
about diagnosis, treatment, stem cell transplantation and post-transplantation outcomes.
This information will be de-identified.
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Observational Model: Cohort, Time Perspective: Retrospective
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