Hodgkin Lymphoma Clinical Trial
— AVD-RevOfficial title:
Phase I Trial of AVD Plus Lenalidomide (Revlimid) in Elderly Intermediate or Advanced Stage Hodgkin Lymphoma Patients
| Verified date | March 2018 |
| Source | University of Cologne |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
The purpose of this study is to determine within the scope of the trial what the maximum tolerated dose (MTD) of lenalidomide in combination with AVD should be.
| Status | Completed |
| Enrollment | 30 |
| Est. completion date | February 2016 |
| Est. primary completion date | April 2014 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 60 Years to 75 Years |
| Eligibility |
Inclusion Criteria: - Hodgkin Lymphoma, intermediate or advanced stage - Age >60 and <75 years - ECOG 2 or better - No major organ dysfunction - Ability to take aspirin or LMW Heparin Exclusion Criteria: - HL as composite lymphoma - Prior use of lenalidomide - Prior use of chemo- or radiotherapy |
| Country | Name | City | State |
|---|---|---|---|
| Germany | 1st Dept. of Medicine, Cologne University Hospital | Cologne | NRW |
| Lead Sponsor | Collaborator |
|---|---|
| University of Cologne |
Germany,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Dose limiting toxicities (DLT) | |||
| Secondary | Overall response rate (ORR) | |||
| Secondary | Progression free survival (PFS) | 2 years |
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