Hodgkin Disease Clinical Trial
Official title:
A Pilot Study of Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplantation in Patients With Relapsed/Refractory Hodgkin Lymphoma
The purpose of this study to evaluate the feasibility of lenalidomide maintenance therapy in patients with relapsed Hodgkin lymphoma after autologous transplant
Primary Objectives -To evaluate the feasibility of lenalidomide maintenance therapy in patients with relapsed Hodgkin lymphoma after autologous stem cell transplant, as measured by dropout rate. Secondary Objectives - To assess overall survival, event free survival, and progression free survival. - To establish the adverse event profile of long-term maintenance therapy with lenalidomide in this patient population. - To assess the conversion of partial response/stable disease post-ASCT to complete response. - To evaluate changes in immune cell number and function and plasma proteins before, during, and after lenalidomide therapy (correlative studies). ;
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