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Hoarseness clinical trials

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NCT ID: NCT05892770 Enrolling by invitation - Spasmodic Dysphonia Clinical Trials

Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia

Start date: August 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

One initial study has shown that Botulinum Toxin (BT) in combination with zinc supplementation may increase the duration of effects BT treatment. This initial study was in the context of facial aesthetics. The purpose of the present study is to determine the effect, if any, of oral zinc supplementation prior to BT in the treatment of spasmodic dysphonia. If positive effects will be observed, this would help reduce the burden of disease for these patients.

NCT ID: NCT05878197 Completed - Dysphonia Clinical Trials

Effect of Semi-occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold Nodules

Start date: July 29, 2019
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to determine and compare the effects of different voice therapy programs in children with vocal fold nodules. Vocal fold nodules are non-cancerous growths on the vocal folds which cause hoarseness. The main questions this trial aims to answer are: - What are the short-term effects of the new voice therapy program 'straw phonation' and a more traditional 'resonant voice therapy' program on (a) the vocal quality, (b) the size of the growths on the vocal folds, and (c) the overall functioning in children with vocal fold nodules? During straw phonation exercises, you make sound through a drinking straw. During resonant voice therapy exercises or 'humming', you make an 'm' sound as you breathe out. - What are the long-term effects of these voice therapy programs? Participants will receive a short-term intensive voice therapy program of four days. The researchers will compare the straw phonation group, resonant voice therapy group and control group to see if voice therapy works well in treating children with vocal fold nodules. The researchers hypothesize that straw phonation will have better results than resonant voice therapy. Straw phonation exercises are easier for children because they use an external tool (the straw) and less self-correction is needed.

NCT ID: NCT05580302 Recruiting - Spasmodic Dysphonia Clinical Trials

Cortical Silent Period in Laryngeal Dystonia

cSPDystonia
Start date: October 10, 2022
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to evaluate the cortical silent period (cSP) in cricothyroid muscle (CT) in laryngeal dystonia and control healthy subjects. The study will provide norms related to latency and amplitude of motor evoked potentials (MEPs) and duration of cSP in CT muscle in laryngeal dystonia and control healthy subjects. Findings may give a baseline in comparison to findings in laryngeal diseases and insight into maladaptive cortical control function during phonation in laryngeal diseases like laryngeal dystonia.

NCT ID: NCT05531617 Completed - Sore-throat Clinical Trials

A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for Intubation

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to compare the incidence of postoperative sore throat after intubation with two different types of laryngoscopes.

NCT ID: NCT05467228 Not yet recruiting - Laryngeal Dystonia Clinical Trials

Laryngeal Vibro-tactile Stimulation as a Non-invasive Symptomatic Treatment for Spasmodic Dysphonia

Start date: January 1, 2025
Phase: Phase 2
Study type: Interventional

The general aim of the research is to provide scientific evidence that vibro-tactile stimulation (VTS) represents a non-invasive form of neuromodulation that can induce measurable improvements in the speech of patients with laryngeal dystonia (LD) - also called spasmodic dysphonia (SD).

NCT ID: NCT05410756 Completed - Fibromyalgia Clinical Trials

Relationship Between Dysphonia And Anxiety In Fibromyalgia

Start date: March 1, 2022
Phase:
Study type: Observational

Our aim in conducting this study is to determine the relationship between voice disorders and anxiety in patients with fibromyalgia syndrome (FS).

NCT ID: NCT05383417 Completed - Dysphagia Clinical Trials

No Post Intubation Laryngeal Symptoms

No-PILS
Start date: November 8, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and trouble swallowing.

NCT ID: NCT05365126 Recruiting - Clinical trials for Muscle Tension Dysphonia

Complete Vocal Technique Voice Therapy for Muscle Tension Dysphonia (CVT4MTD)

CVT4MTD
Start date: May 5, 2022
Phase: N/A
Study type: Interventional

This proof-of-concept study is designed to evaluate whether a pedagogic technique used to help performers, known as the Complete Vocal Technique (CVT), can be used to help patients with a type of voice disorder known as Muscle Tension Dysphonia (MTD). MTD is responsible for up to 40% of patients presenting with voice and throat complaints. MTD is due to inefficient or ineffective voice production resulting from an imbalance in the control of the breathing mechanism, and uncontrolled constriction of the muscles in the larynx (voice box) or vocal tract (throat space above the vocal cords). Standard treatment is Voice Therapy delivered by a specialist Speech Therapist (SLT-V) often using a video link (telepractice aka telehealth). CVT is widely used in Europe by singers and vocal coaches. Practitioners (CVT- Ps) undergo a three-year accredited training programme, and the systematic and structured approach helps healthy singers and other performers optimise the function of the voice to produce any sound required. It also helps if the performer has vocal problems, which are also mainly due to uncontrolled throat constrictions. The purpose of this pilot study is to see if the CVT voice therapy approach (CVT-VT) can help, and offers advantages, to standard SLT-V methods in the treatment of patients with MTD. Ten adult patients will be recruited from the Voice clinic at Nottingham University Hospital. Participants will have a multidimensional assessment using questionnaires, and voice recordings and then receive up to 6 video sessions of CVT-VT delivered using a video link by a CVT-P. The participants will then be reviewed back in clinic at 8 weeks and be reassessed, using further questionnaires and analysis of the voice pre- and post-therapy recordings, to evaluate the outcome of this treatment approach. Qualitative methodology will determine whether CVT-VT offers any therapeutic advantages to existing SLT-VT treatment methods.

NCT ID: NCT05357222 Recruiting - Voice Disorders Clinical Trials

Straw Phonation Exercise Program for Pitch Extension

SOVT
Start date: November 16, 2021
Phase: N/A
Study type: Interventional

To investigate the change in fundamental frequency range and vocal fold stability achievable with vocal fold stretching exercise in human populations with high and low vocal activity

NCT ID: NCT05317156 Not yet recruiting - Dysphagia Clinical Trials

The Effect of Cold Vapor on Intubation-Related Symptoms and Comfort in the Early Postoperative Period

Start date: April 18, 2022
Phase: N/A
Study type: Interventional

Endotracheal Intubation (EI) is performed in order to monitor the effectiveness of anesthesia and to control the patient's breathing during the surgery under general anesthesia. In EI, which is an invasive procedure, damage to the larynx and trachea may occur during the placement of the endotracheal tube or due to long-term use. Complications such as postintubation ulcer, laryngeal nerve paresis, arytenoid dislocation may develop in the early period due to EI, and patients may have complaints such as sore throat, swallowing problems, hoarseness, and cough in the postoperative period. This affects the comfort of the patients in the postoperative period. For this reason, it is important to prevent intubation-related symptoms of patients who will undergo surgical intervention before they occur.