Hoarding Clinical Trial
Official title:
Transcranial Magnetic Stimulation Treatment of Hoarding Disorder
This is multiple baseline study including up to three participants with a primary diagnosis of hoarding disorder. All patients will receive unblinded rTMS study intervention.
Study assessments will be conducted at pretreatment, weekly during baseline assessment (until a stable baseline is established, but not less than 2, 4, and 6 weeks for patients respectively), weekly during treatment, and at posttreatment. Magnetic resonance imaging (MRI) will be competed at prebaseline, pretreatment, and posttreatment. Treatment will entail daily (5 days/week) sessions of rTMS using the Neurostar Therapy System for 6 weeks employing right-sided, low frequency stimulation (1 Hz, 900 pulses/session for 30 sessions, 27,000 total pulses, intensity at 90% of the passive motor threshold) to the dorsolateral prefrontal cortex (DLPFC). Neuronavigation will direct coil placement over the DLPFC based upon structural MRI. ;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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