Neural Mechanisms of Decision Making in Hoarding Disorder

Hoarding Disorder Clinical Trial

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Official title:

Neural Mechanisms of Decision Making in Hoarding Disorder

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03487224
• Other study ID #: 42327
• Status: Active, not recruiting
• Start date: July 8, 2018
• Est. completion date: May 30, 2024

Study information

• Verified date: April 2024
• Source: Stanford University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Description:

Hoarding disorder is a common and disabling disorder that represents a significant public health problem. This study aims to build on current research on decision making by examining these processes in hoarding disorder.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 25
• Est. completion date: May 30, 2024
• Est. primary completion date: May 30, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Identify inclusion criteria.

Inclusion criteria for participants diagnosed with HD:

1. ages 18-70

2. primary diagnosis of hoarding disorder

3. sufficient severity of hoarding symptoms

4. stable on psychotropic medications for 1 month prior to study enrollment

5. capacity to provide informed consent

6. ability to tolerate clinical study procedures

Inclusion criteria for healthy control participants:

1. ages 18-70

2. capacity to provide informed consent Identify exclusion criteria.

Exclusion criteria for participants with HD:

1. psychiatric or medical conditions that make participation unsafe

2. pregnant or nursing females

3. concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)

4. presence of metallic device or dental braces

Exclusion criteria for healthy control participants:

1. any current or lifetime psychiatric diagnosis

2. current or past use of psychotropic medication

3. pregnant or nursing females

4. major medical or neurological problem

5. presence of metallic device or dental braces

Related Conditions & MeSH terms

• Hoarding Disorder

Intervention

Device:
• MRI with fMRI frequency
Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

Locations

Country	Name	City	State
United States	Stanford University	Stanford	California

Sponsors (1)

Lead Sponsor	Collaborator
Stanford University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	BOLD signal	BOLD signal derived from fMRI	up to 90 minutes

External Links

•   Rodriguez Lab Website
•   Stanford Medicine Faculty Page