RETRIeVE: ReversE TranscRiptase Inhibitor hiV Practice

HIV Positive Clinical Trial

Official title:

Non-nucleoside Reverse Transcriptase Inhibitor Failure in a High HIV Caseload Australian Primary Care Practice

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01154556
• Other study ID #: RETRIeVE
• Status: Completed
• Phase: N/A
• First received: June 30, 2010
• Last updated: September 17, 2015
• Start date: June 2010
• Est. completion date: February 2013

Study information

• Verified date: September 2015
• Source: Holdsworth House Medical Practice
• Contact: n/a
• Is FDA regulated: No
• Health authority: Australia: Human Research Ethics Committee
• Study type: Observational

Clinical Trial Summary

An observational retrospective study of NNRTI experienced patients who have virologically failed. The study aims to assess resistance profiling and subsequent prescription patterns of patients on NNRTIs

Description:

This is a cross-sectional study involving retrospective review of HIV-1 positive patient records who began treatment with a non-nucleoside reverse transcriptase inhibitor (NNRTI) and subsequently failed. Patients who have virologically failed previous NNRTI treatment, or have resistance to 1 drug in the NNRTI class are examined further. Such patients will have attended the clinic every 3-6 months for routine medical care. The data source for variables collected is the patient's electronic medical records. This database is located at Holdsworth House Medical Practice (HHMP), Sydney.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2044
• Est. completion date: February 2013
• Est. primary completion date: September 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

1. Documented HIV infection

2. Attended Holdsworth House Medical Practice 1999-2009.

3. Chosen ART regime includes an NNRTI

Exclusion Criteria: N/A

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

• HIV Positive
• HIV Seropositivity

Locations

Country	Name	City	State
Australia	Holdsworth House Medical Practice	Darlinghurst	New South Wales

Sponsors (1)

Lead Sponsor	Collaborator
Holdsworth House Medical Practice

Country where clinical trial is conducted

Australia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	resistance profiling and subsequent prescription patterns of patients on NNRTIs		1 year	No