Study of Novel Antiretrovirals in Participants With HIV-1

Status Active, not recruiting

Clinical Trial Summary

Master protocol: The goal of this master clinical trial study is to learn how novel antiretrovirals (medicines that stop the virus from multiplying) affect the human immunodeficiency virus-1 (HIV-1) infection in people living with HIV (PWH). Substudy-01 (GS-US-544-5905-01) will evaluate bavtavirine in PWH. Substudy-02 (GS-US-544-5905-02) will evaluate GS-1720 in PWH. Substudy-03 (GS-US-544-5905-03) will evaluate GS-6212 in PWH.

Clinical Trial Description

This umbrella study will begin with a substudy of bavtavirine (Substudy-01), and new substudies may be added in the future. Substudies evaluating additional study drugs will be added in a staggered manner when relevant nonclinical and/or clinical data become available. - Substudy-01 enrollment closed, actual enrollment is 13. - Substudy-02 enrollment closed, actual enrollment is 28. - Substudy-03 enrollment closed, actual enrollment is 8. ;

Study Design

Related Conditions & MeSH terms

HIV-1-infection

Clinical Trial Details

NCT number	NCT05585307
Study type	Interventional
Source	Gilead Sciences
Contact
Status	Active, not recruiting
Phase	Phase 1
Start date	October 26, 2022
Completion date	March 2027

View Details

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