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Histiocytic Disorders clinical trials

View clinical trials related to Histiocytic Disorders.

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NCT ID: NCT02649972 Completed - Clinical trials for Histiocytic Disorders

Single-agent Cobimetinib for Adults With Histiocytic Disorders

Start date: January 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out what effects, good or bad, Cobimetinib has in patients with histiocytosis. Cobimetinib is an investigational oral medication that blocks MEK1.

NCT ID: NCT02608619 Completed - Clinical trials for Langerhans Cell Histiocytosis

Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement

Start date: November 2015
Phase:
Study type: Observational

The main purpose of this study is to discover how 18F-cholineFCH distributes in the body, and see if it can distinguish active histiocytes (tumor) from inflammatory (non- tumor) cells. This tracer has the potential to give the investigators' team more information when trying to identify the tumor cells that are most important to collect with biopsy. In addition, the study will measure levels of 18F-cholineFCH in the biopsy tissue.