High-resolution CE-MRA of Children's Hip Joint

Hip Clinical Trial

Official title:

High-resolution Contrast-enhanced Magnetic Mesonance Angiography of Children's Hip Joint

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05754905
• Other study ID #: CQMU-2023-2
• Status: Completed
• Start date: January 1, 2021
• Est. completion date: January 31, 2023

Study information

• Verified date: February 2023
• Source: Children's Hospital of Chongqing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this observational study is to learn about the feasibility of enhanced three-dimensional water-selective cartilage (3D-WATSc) sequence in displaying the vessels of children's hip by magnetic resonance. The main questions it aims to answer are:

• Could the images of enhanced 3D-WATSc sequence show the healthy side hip joint vessels in children?

• Could the images of enhanced 3D-WATSc sequence show the vascular disease of the suffering side hip joint in children?

Participants with unilateral hip disease will undergo the magnetic resonance examination including enhanced 3D-WATSc sequence. The pelvic plain film and magnetic resonance images will be collected and analysed.

Researchers will compare the images of of the normal side with the images of the abnormal side to see if the enhanced 3D-WATSc sequence images could show the vascular disease of the suffering side hip joint in children?

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: January 31, 2023
• Est. primary completion date: December 30, 2022
• Gender: All
• Age group: 6 Months to 14 Years

Eligibility

Inclusion Criteria:

• Children aged 6 months-14 years who are diagnosed as hip disease after screening by pediatric orthopedic surgeon in Children's Hospital of Chongqing Medical University during the study period. The hip disease contain developmental dysplasia of the hip, Perthes disease, infection of the hip, inflammation of the hip, fracture of the hip, and Meyer's dysplasia.

Exclusion Criteria:

• patients with bilateral hip joint disease; patients with claustrophobia;Patients with metal implants (such as pacemaker implantation)

Related Conditions & MeSH terms

• Hip
• Magnetic Resonance
• Vessels; Anomaly

Intervention

Other:
• Magnetic resonance examination
the two groups are underwent magnetic resonance examination including enhanced 3D-WATSc sequence

Locations

Country	Name	City	State
China	Children's Hospital of Chongqing Medical University	Chongqing	Chongqing

Sponsors (1)

Lead Sponsor	Collaborator
Children's Hospital of Chongqing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The medial circumflex femoral artery (MCFA) and lateral circumflex femoral artery (LCFA) of the bilateral hip joint	Morphology of the MCFA and LCFA of the bilateral hip joint	1 day (Magnetic resonance examination end time)
Primary	The branches of the MCFA and/or LCFA around the bilateral femoral neck	Morphology of MCFA and/or LCFA branches around the bilateral femoral neck	1 day (Magnetic resonance examination end time)
Primary	The vessels of secondary ossification center and/or cartilaginous vascular canal in bilateral femoral head	Morphology of the vessels and cartilaginous vascular canal in bilateral femoral head	1 day (Magnetic resonance examination end time)