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Hip Replacement Surgery clinical trials

View clinical trials related to Hip Replacement Surgery.

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NCT ID: NCT06307145 Completed - Clinical trials for Hip Replacement Surgery

Korea Hip Replacement Surgery Registry

Start date: January 1, 2003
Phase:
Study type: Observational

This cohort study obtained data from the Korean National Health Insurance Service (K-NHIS) database. For the hip replacement registry, we included all adult patients older than 19 who received total or hemiarthroplasty surgery between January 1, 2003, and December 31, 2019. Using this registry, we compared efficacy and safety by type of head or liner.

NCT ID: NCT05950646 Recruiting - Dexmedetomidine Clinical Trials

Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality

Start date: November 1, 2023
Phase: Phase 4
Study type: Interventional

Sleep disturbances are prevalent in older patients with osteoarthrosis or fracture who are scheduled for knee or hip replacement surgery. The occurrence of sleep disturbances is associated with worse outcomes including increased risk of delirium and cardiac events, and worsened functional recovery. Dexmedetomidine is a highly selective α2-adrenergic agonist with sedative, anxiolytic, and analgesic properties. It exerts sedative effects via activating the endogenous sleep pathways and produces a state like non-rapid eye movement sleep, which is different from opioid- and benzodiazepine-induced sedation. Esketamine is a N-methyl-D-aspartic acid receptor antagonist and has been used as an anesthetic and analgesic. Recent studies showed that low-dose esketamine has anti-depressive and sleep-promoting effects. The investigators suppose that mini-dose dexmedetomidine-esketamine combined infusion at night can improve perioperative sleep quality in patients scheduled for knee or hip replacement surgery.

NCT ID: NCT05246007 Not yet recruiting - Dexmedetomidine Clinical Trials

Nocturnal Low-dose Dexmedetomidine Infusion and Perioperative Sleep Quality

Start date: May 2022
Phase: N/A
Study type: Interventional

Sleep disturbances are prevalent in older patients with osteoarthrosis or fracture scheduled for knee or hip replacement surgery. The occurrence of sleep disturbances is associated with worse outcomes including increased risk of delirium and cardiac events, and worsened functional recovery. Dexmedetomidine is a highly selective α2-adrenergic agonist with sedative, anxiolytic, and analgesic properties. It exerts sedative effects via activating the endogenous sleep pathways and produces a state like non-rapid eye movement sleep, which is different from opioid- and benzodiazepine-induced sedation. Night-time infusion of low-dose dexmedetomidine may improve sleep quality. However, evidence in this aspect is limited.

NCT ID: NCT00161902 Completed - Clinical trials for Hip Replacement Surgery

Efficacy and Safety of Fibrin Sealant Vapor Heated Solvent/Detergent Treated (FS VH S/D) for Hemostasis in Subjects Undergoing Total Hip Replacement

Start date: August 2001
Phase: Phase 3
Study type: Interventional

The purpose of the study is to monitor the safety of FS VH S/D and evaluate whether FS VH S/D is superior to standard treatment in reducing blood loss in subjects undergoing total hip replacement with cement-free hip prostheses.