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NCT03532919 Clinical Trial

Heart and Renal Failure in Hip Fracture Surgery

Hip Fractures Clinical Trial

Official title:
Heart and Renal Failure in Hip Fracture Surgery

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03532919
Other study ID # Refhina
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 1, 2018
Est. completion date December 1, 2018

Study information
Verified date December 2018
Source Sahlgrenska University Hospital, Sweden
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as well as renal failure noted by Changes in Serum Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

Description:

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as awell as renal failure noted by Changes in S Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as a step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

Recruitment information / eligibility
Status Completed
Enrollment 105
Est. completion date December 1, 2018
Est. primary completion date August 1, 2018
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- Hip fracture patient to be operated upon Classified as being ASA 3 or more

Exclusion Criteria:

- Not forfilling inclusion Criterias

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Serum Tropinin
Blodsamples will be taken 4 times from preoperatively to 2 Days postoperatively

Locations
Country Name City State
Sweden Sahlgrenska University Hospital Molndal Vastra Gotaland

Sponsors (1)
Lead Sponsor Collaborator
Sahlgrenska University Hospital, Sweden

Country where clinical trial is conducted

Sweden, 

Outcome
Type Measure Description Time frame Safety issue
Primary Mortality post surgery 90 days
Secondary Serum concentrations of Troponin, NTproBNP, Creatinin and Cystatin C Relations between values and mortality at 30 and 90 days 90 days
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