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Hip Fractures clinical trials

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NCT ID: NCT00280267 Completed - Muscle Weakness Clinical Trials

Testosterone Therapy After Hip Fracture in Elderly Women

Start date: August 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the feasibility of testosterone replacement therapy in frail elderly female hip fracture patients who have testosterone deficiency, and to obtain preliminary information about the effects of testosterone therapy on muscle strength and size, bone density, mobility, daily functioning, and quality of life.

NCT ID: NCT00250237 Completed - Hip Fracture Clinical Trials

Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery

Start date: November 2005
Phase: Phase 3
Study type: Interventional

In this study the investigators want to determine if treatment with haloperidol direct post-operatively after acute hip surgery in high risk patients protects against developing a post-operative delirium.

NCT ID: NCT00224367 Completed - Fractured Hip Clinical Trials

Does Early Ambulation After Hip Fracture Surgery Accelerate Recovery?

Start date: February 2004
Phase: N/A
Study type: Interventional

Hip fractures are a significant problem for healthcare providers due to the increasing incidence of fractures in an ageing population. Hip fracture is the most frequent fracture for people over 80 years of age and the second most frequent for those over 65 years. It is projected that by 2051, 23% of the Australian population will be older than 65 and the number of hip fractures will rise fourfold (17,000 in 2004, to 60,000 in 2051). Evidence-based clinical practice guidelines regarding management of hip fracture were published in the Medical Journal of Australia in 1999 and updated in 2003. Seventeen aspects of treatment were systematically reviewed, including mobilisation after surgery. Early assisted ambulation within 48 hours post surgery was recommended (Chilov 2003 p 490). However, the recommendation was based on observational (level 3) evidence only. Early mobilization post surgery is resource intensive. Early mobilization is challenging and uncomfortable for the patient and requires the assistance of one or sometimes two, physiotherapists available seven days per week. Benefits must be rigorously evaluated to justify recommendation. We undertook a randomized controlled trial of the effect of two different ‘time to first ambulation’ intervals after hip fracture surgery on patient and hospital outcomes.Our hypothesis was that early mobilisation would accelerate functional recovery after hip fracture surgery.

NCT ID: NCT00197496 Completed - Hip Fracture Clinical Trials

Body Weight Supported Treadmill Training Following Hip Fracture

Start date: January 2007
Phase: N/A
Study type: Interventional

Achieving independent ambulation is an important goal of hip fracture rehabilitation, as it is predictive of returning to the community and of future health problems. Current research regarding post-hip fracture rehabilitation is sparse. Body weight supported treadmill training (BWSTT) is a novel approach to retrain walking abilities. BWSTT may be ideal for retraining walking after hip fracture, as it is task-specific and alleviates the demands of maintaining balance while walking skills are trained. The use of the harness may provide a sense of security for the patient, facilitating walking training. The proposed project will investigate the feasibility and tolerability of BWSTT after hip fracture, and its impact on function, mobility, quality of life and fear of falling. It is hypothesized that BWSTT 3-5 times weekly in acute hip fracture patients will improve function, mobility, quality of life and reduce fear of falling.

NCT ID: NCT00175175 Completed - Osteoporosis Clinical Trials

Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients

Start date: March 2002
Phase: N/A
Study type: Interventional

Patients with hip fractures have suffered the most devastating consequence of osteoporosis; and yet, they are rarely if ever tested or treated for the condition, even though they remain at high risk of recurrent fracture. We hypothesize that, compared with usual care, an allied health professional-run osteoporosis service (case management) will be able to increase testing and treatment of osteoporosis in patients at high risk of fracture.

NCT ID: NCT00162630 Completed - Hip Fracture Clinical Trials

Fascia Iliaca Compartment Blockade as Analgesia for Hip Fractures in the Acute Phase

Start date: May 2003
Phase: Phase 4
Study type: Interventional

To evaluate the analgesic potential of an neural blockade (Fascia iliaca compartment) with local anaesthetics in patients with hip fracture immediately after arrival in the emergency department.

NCT ID: NCT00155597 Completed - Hip Fractures Clinical Trials

The Outcome and Cost Analysis of Home-care Physical Therapy for Postoperative Hip Fracture Patients

Start date: August 1999
Phase: N/A
Study type: Interventional

The aims of this study are: 1. To develop a disease-specific questionnaire for hip fractures. 2. To find the influences of physical therapy (PT) on patients' function and health-related quality of life (HRQL). 3. To estimate the quality adjusted life years (QALY) of cases of hip fracture with or without the PT program by a quality-adjusted survival (QAS) method. 4. To perform cost effectiveness analysis (CEA) to evaluate the effectiveness of PT and as a base to compare it with other health intervention programs. At the beginning of the study, the investigators will develop the disease-specific questionnaire for hip fractures. Cases of patients with hip fractures hospitalized in orthopedic wards of the National Taiwan University Hospital (NTUH) and Chung-Hsing Hospital of Taipei from August 1, 1989 to July 31, 1999 are the study population during the first year of this study. According to their receiving PT or not during hospitalization, the patients are assigned to a PT or non-PT group. The identification (ID) numbers will be matched with the death certificate file of the Department of Health to verify the survival status. Furthermore, 30 cases per group per year will be randomly sampled to interview their HRQL and evaluate their function with the disease-specific questionnaire for hip fractures. Combining the survival function and HRQL, the QALY could be estimated. Cases of hip fracture admitted to the orthopedic ward of NTUH and receiving a PT program from January 1, 2000 will be the second-year study population in this study. They will be randomly assigned to a group of follow-up PT (group I) or non-follow-up PT (group II). The patients assigned to group I will have a 4-time PT evaluation and treatment at home after discharge from the hospital (1 week, 1 month, 3 months and 6 months after discharge). All patients will be evaluated at discharge, 1 month, 6 months, and 1 year after discharge to follow their survival status, functional status and HRQL. The expected results of this study will be to develop the disease-specific questionnaire for hip fractures, to show the functional outcomes of cases of hip fracture, and to estimate the QALY of them.

NCT ID: NCT00136058 Completed - Osteoporosis Clinical Trials

Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients

Start date: January 2002
Phase: Phase 3
Study type: Interventional

The objective of this study is to determine if an intervention with a fracture manager to arrange bone densitometry after a hip fracture is more effective in diagnosing and treating osteoporosis when compared to "usual care". "Usual care" consists of no intervention to arrange bone mineral density (BMD) testing or therapy other than what normally occurs in the community. The investigators postulate that a fracture manager will be more effective in getting BMD done and in starting appropriate therapy.

NCT ID: NCT00119457 Completed - Clinical trials for Venous Thromboembolism

Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)

Start date: January 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether TTP889 prevents venous thromboembolism following surgery to repair hip fracture.

NCT ID: NCT00058864 Completed - Hip Fractures Clinical Trials

The HIP Impact Protection Program (HIP PRO)

Start date: September 2001
Phase: N/A
Study type: Interventional

HIP PRO is a multicenter randomized, controlled trial of an energy absorbing and distributing padding system designed to reduce the incidence of hip fractures in 546 nursing home (NH) residents. The trial is being conducted in three geographic regions of the US: Boston, St. Louis, and Baltimore. Non bed- or chair-bound residents over the age of 65 are given protective underwear containing a single pocket and hip pad so that each resident becomes his/her own control. During the trial, hip fracture incidence will be compared in padded and unpadded hips using an intent to treat analysis. A secondary aim is to identify resident and facility factors contributing to non-adherence with the use of the hip protector.