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Hip Fractures clinical trials

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NCT ID: NCT00597779 Completed - Hip Fractures Clinical Trials

Randomized Comparison of 2 Fixation Techniques for Unstable Intertrochanteric Hip Fractures

EMvsIM
Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the clinical and radiological outcome of patients that are treated with two different orthopedic implants. The study population will consist of patients that have sustained unstable hip fractures. The two different implants will be randomly assigned. The null hypothesis states that there should not be any significant differences between the two implants.

NCT ID: NCT00592813 Completed - Hip Fracture Clinical Trials

Efficacy of a Post-Rehabilitation Exercise Intervention

Start date: April 2008
Phase: N/A
Study type: Interventional

Background: Many people who have suffered a hip fracture are discharged from rehabilitation services with significant residual functional limitations and disability. We believe that a home-based exercise program that incorporates cognitive-behavioral techniques to increase exercise adherence and promote the return to daily activities could extend the benefits of formal rehabilitation for patients who have suffered a hip fracture. Specific Aims: We will conduct a 5-year multi-site randomized controlled trial in patients who have suffered a recent hip fracture and have completed all rehabilitation services. The specific aim that this project will address is whether: Participation in the Strong for Life (SFL) program will improve function and disability outcomes in participants 6-months after they are discharged from rehabilitation services. This study will also investigate the following secondary hypotheses: 1. Changes in function and disability at 6-month follow-up will be correlated with changes in all three proposed intermediary variables: muscle strength, balance, and self-efficacy. 2. The SFL program will significantly improve health-related quality of life among participants at 6-month follow-up. 3. At 9-month follow-up the SFL program will continue to have a significant impact on participants' function and disability compared to the control group. Target population: The target population will be people aged 60 years or more who have suffered a recent traumatic hip fracture, have one or more residual functional limitations and have completed all inpatient, outpatient or homecare rehabilitation services. Intervention: We will use an enhanced version of the Strong for Life program. This home-based exercise program will include both resistance exercises using Thera-bands that will be shown on a video/DVD and weight-bearing exercises that are progressed using a step and/or a weighted vest. A cognitive-behavioral program that is customized for people recovering from hip fracture is being developed that will focus on promoting exercise adherence, decreasing fear of falling and increasing the return to daily activities in the patient's home and community. Design: A randomized controlled clinical trial will be implemented to measure the efficacy of the Strong for Life program. An attention-control intervention will be provided to all participants assigned to the control group. The outcome evaluation points are: - T0: baseline, at the point of discharge from formal rehabilitation; - T2: 6-month outcome assessment - T3: 9-month follow-up Outcomes: The primary outcomes will be function measured by both self-report (AM PAC) and physical performance measures (SPPB). Secondary outcomes include disability, self-efficacy, balance, strength, cognition, and reaction time. Adherence to the exercise program and adverse events will also be monitored.

NCT ID: NCT00590707 Completed - Delirium Clinical Trials

Post-Operative Delirium in Elderly Surgical Patients

STRIDE
Start date: January 2005
Phase: N/A
Study type: Interventional

This research is being done to see what effects sedative drugs during surgery have on peoples' thinking processes after they wake up.

NCT ID: NCT00582972 Completed - Osteoporosis Clinical Trials

Does Omeprazole Decrease Intestinal Calcium Absorption?

Start date: January 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.

NCT ID: NCT00564434 Completed - Delirium Clinical Trials

Postoperative Delirium in Hip Fracture Patients

Start date: May 2005
Phase: N/A
Study type: Observational

Risk factors for postoperative delirium in hip fracture patients.

NCT ID: NCT00556842 Completed - Hip Fractures Clinical Trials

Comparing Total Hip Arthroplasty and Hemi-Arthroplasty on Secondary Procedures and Quality of Life in Adults With Displaced Hip Fractures

HEALTH
Start date: March 2009
Phase: N/A
Study type: Interventional

Each year, hip fracture, an injury that can impair independence and quality of life, occurs in about 280,000 Americans and 36,000 Canadians. By the year 2040, the annual healthcare costs associated with hip fractures are expected to reach $9.8 billion in the United States and $650 million in Canada. It is important to have in place optimal practice guidelines for the surgical handling of this injury. One type of hip fracture, called a displaced femoral neck fracture, is often treated with a hip replacement surgery. Patients undergoing a hip replacement may receive either a total hip replacement, in which the head of the femur and the hip joint socket are replaced, or a partial hip replacement, in which only the head of the femur is replaced. This study will compare the two different hip replacement procedures to determine which one results in better outcomes after surgery in adults aged 50 and older.

NCT ID: NCT00555945 Completed - Clinical trials for Femoral Neck Fractures

Re-Evaluation of GAmma3 Intramedullary Nails in Hip Fracture (REGAIN)

REGAIN
Start date: May 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the impact of Gamma3 intramedullary nails versus sliding hip screws on rate of revision surgery in individuals with inter-trochanteric fractures. Secondary outcomes include fracture healing rates, fracture related complications, and health-related quality of life.

NCT ID: NCT00523575 Completed - Malnutrition Clinical Trials

Nutritional Intervention in Hip Fracture Patients

Start date: August 2007
Phase: N/A
Study type: Interventional

Hip fractures are highly prevalent and are expected to increase due to the ageing population. Malnutrition is often present in these patients and is associated with prolonged convalescence, lower mobility, lower mental function, lower quality of life and higher complication rate. Nutritional intervention starting soon after hospital admission might reduce complication rate and total length-of-stay by improving nutritional and functional status. Research questions are: 1. Does nutritional intervention reduce total length-of-stay? 2. Is nutritional intervention cost-effective? 3. Can nutritional screening contribute to targeting of nutritional intervention, and thereby reduce costs without loss of effectiveness? Patients randomized to the intervention group will receive oral nutritional supplements (protein and energy enriched) and regular dietetic counselling during hospitalisation and after discharge at patients' homes for 3 months. Patients in the control group will receive usual nurse and dietetic care. Outcome measurements will be taken at baseline, 3 months and 6 months after inclusion.

NCT ID: NCT00497978 Completed - Insulin Resistance Clinical Trials

The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Patient

TAUP
Start date: March 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to reduce the postoperative morbidity and mortality in the elderly hip fracture patient, by giving them taurine peri-operatively.

NCT ID: NCT00424619 Completed - Hip Fracture Clinical Trials

A Randomised, Controlled Comparison of Vitamin D Strategies is Acute Hip Fracture Patients

Start date: October 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine the best dose of Vitamin D to give to hip fracture patients to achieve the optimal therapeutic level.