Clinical Trials Logo

Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT05998720
Other study ID # ZDWY.FSK.025
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date July 1, 2023
Est. completion date June 13, 2024

Study information

Verified date August 2023
Source Fifth Affiliated Hospital, Sun Yat-Sen University
Contact Xiaojun Chen
Phone +8615820587112
Email 422175400@qq.com
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

Explore the imaging and quantitative monitoring of hip bone, cartilage and ligament by magnetic resonance UTE technology, combined with QCT and DXA technology, to provide a more accurate basis for clinical evaluation and treatment.


Description:

Osteoporosis is a systemic bone metabolism-related disease characterized by decreased bone mass per unit volume, increased bone fragility, decreased bone density, thinning of the bone cortex and changes in bone microstructure. It often occurs in the lumbar spine and hip joint. Femoral neck fracture is a common complication of hip osteoporosis, which seriously affects people's quality of life. UTE technology can clearly image and quantify human cortical bone and cancellous bone, and advanced UTE technology such as STAIR-UTE and UTE-MT have made some progress in the field of osteoporosis. The purpose of this study was to explore UTE technology for imaging and quantitative study of cortical bone, cancellous bone and cartilage of hip joint, and to find more accurate imaging methods for clinical evaluation of hip osteoporosis and other diseases.


Recruitment information / eligibility

Status Recruiting
Enrollment 150
Est. completion date June 13, 2024
Est. primary completion date June 13, 2024
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: 1. Patients with past or suspected osteoporosis and bone loss; 2. Patients with previous femoral neck fracture; 3. Patients with avascular necrosis of femoral head; 4. Hip osteoarthritis patients. Exclusion Criteria: 1. Patients with metal implants in corresponding parts; 2. Claustrophobic.

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
China Radiography department Zhuhai Guangdong

Sponsors (1)

Lead Sponsor Collaborator
Fifth Affiliated Hospital, Sun Yat-Sen University

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary proton density fat fraction (PDFF) Magnetic resonance proton density fat fraction Baseline (before surgery)
Primary T2 relaxation rate R2* Baseline (before surgery)
Primary Magnetization Transfer Ratio (MTR) magnetization transfer ratio Baseline (before surgery)
Primary T1rho spin-lattice relaxation in the rotation ame Baseline (before surgery)
Secondary Subjective rating values rating values Baseline (before surgery)
See also
  Status Clinical Trial Phase
Recruiting NCT05465096 - Treatment of Osteoarthritis of the Hip Joint With Intra-articular Injection of Microfractured Autologous Adipose Tissue Containing Mesenchymal Stromal Cells. N/A
Not yet recruiting NCT04863911 - Comparative Study Between CT Arthrography and MRI Arthrography in Detection of Intra-articular Hip Pathology
Completed NCT06087549 - PENG Block vs. ESP Block for Pediatric Hip Surgery Phase 4
Recruiting NCT06153940 - Everglade Stem, World Cup and World Liner Post Market Clinical Follow-up
Not yet recruiting NCT04123431 - ACE Acetabular Cup UK Multi-centre PMCF Study
Recruiting NCT04123600 - Origin Stem and Logical Cup Post Market Clinical Follow-up
Recruiting NCT04736641 - Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire
Recruiting NCT05446181 - CLIC1 in Patients Presenting PD
Completed NCT03663270 - Hypotension Probability Index in Anesthesia N/A
Completed NCT05944380 - PENG Block for Total Hip Arthroplasty Phase 4
Completed NCT05567523 - Safety Study of Dexmedetomidine in Elderly Under General Anesthesia Phase 4
Completed NCT03432650 - Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy Phase 3
Not yet recruiting NCT04917510 - Evaluating the Efficacy of Erector Spinae Block in Routine Hip Arthroscopy N/A
Completed NCT03550014 - Effectiveness of Physical Therapy Interventions for Low Back Pain Targeting the Low Back Only or Low Back Plus Hips N/A
Completed NCT03248934 - Patient Performed Examination for Patients With Intra-articular Hip Pain N/A
Completed NCT03417934 - Effects of Hip Distraction Without a Perineal Post on Venous Blood Flow and Peripheral Nerve Conduction
Recruiting NCT05361980 - Pediatric Orthopaedic Implant Safety & Efficacy
Recruiting NCT04027140 - MDR - M/L Taper With Kinectiv Technology Stems and Necks
Recruiting NCT04359628 - How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups?
Completed NCT05001100 - A Rehabilitation With Virtual Reality in Patients After Hip Arthroplasty Surgery (VRRS2018) N/A