Influence of Sevoflurane and Desflurane on Postoperative Sore Throat

Hip Arthroplasty Clinical Trial

Official title:

Influence of Sevoflurane and Desflurane on Postoperative Sore Throat

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03259672
• Other study ID #: SevoDesPOST
• Status: Not yet recruiting
• Phase: N/A
• First received: August 21, 2017
• Last updated: August 21, 2017
• Start date: October 1, 2017
• Est. completion date: November 1, 2018

Study information

• Verified date: August 2017
• Source: Keimyung University Dongsan Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This investigation is planned to compare the incidence and severity of postoperative sore throat according to the use of sevoflurane or desflurane.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: November 1, 2018
• Est. primary completion date: October 1, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• ASA I-III

• Patients scheduled for general anesthesia with endotracheal intubation

Exclusion Criteria:

• Difficult airway

• Friable teeth

• Rapid sequence induction

• Recent sore throat

• Recent upper respiratory infection

• Asthma

• Chronic obstructive pulmonary disease

• Chronic cough

• Arrhythmia

• Coronary disease

• Heart failure

• Pregnancy

• Allergy to sevoflurane

• Allergy to desflurane

• Fever after halogenated anesthetics

• Jaundice after halogenated anesthetics

• Malignant hyperthremia

• Allergy to remifentanil

• Friable teeth

• History of head and neck surgery

• Multiple intubation attempts

• Regional anesthetic agents

• Gastric tube

• Dexamethasone

• Severe hypovolemia

Related Conditions & MeSH terms

• Hip Arthroplasty
• Pharyngitis

Intervention

Drug:
• Sevoflurane
Sevoflurane was used as a maintenance anesthetic agent.
• Desflurane
Desflurane was used as a maintenance anesthetic agent.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Keimyung University Dongsan Medical Center

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of participants with postoperative sore throat		At 24 hr
Secondary	Number of participants with postoperative sore throat		At 0, 2, 4 and 24 hr
Secondary	Number of participants with postoperative hoarseness		At 0, 2, 4 and 24 hr
Secondary	Number of participants with postoperative cough		At 0, 2, 4 and 24 hr
Secondary	Number of participants with postoperative nausea		At 0, 2, 4 and 24 hr
Secondary	Number of participants with postoperative vomiting		At 0, 2, 4 and 24 hr
Secondary	Number of participants with additional pain medication		At 0, 2, 4 and 24 hr
Secondary	Visual analogue scale of postoperative pain		At 0, 2, 4 and 24 hr
Secondary	Number of participants with shivering		At 0, 2, 4 and 24 hr
Secondary	Requirements of analgesics		At 0, 2, 4 and 24 hr