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High Risk Cervical Cancer clinical trials

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NCT ID: NCT02853604 Terminated - Clinical trials for Advanced Cervical Cancer

Study of ADXS11-001 in Participants With High Risk Locally Advanced Cervical Cancer

AIM2CERV
Start date: December 15, 2015
Phase: Phase 3
Study type: Interventional

Locally advanced cervical cancer at higher risk for recurrence (HRLACC) following concurrent chemotherapy and radiation therapy. This is a group of participants with a significant unmet need. The estimated probability of disease recurrence or death within 4 years of diagnosis is 50% and the prognosis is very grave for those who experience a recurrence. The purpose of the study was to compare the disease free survival (DFS) of ADXS11-001 to placebo administered following cisplatin-based combination chemotherapy and radiation (CCRT) with curative intent in participants with HRLACC.