High-Intensity Interval Training Clinical Trial
— HomeHITOfficial title:
A Randomised Control Trial to Assess the Efficacy of Short-term, Home-based High- Intensity Interval Training (HIT) for Improving Indices of Cardiorespiratory Fitness
Verified date | August 2020 |
Source | University of Nottingham |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will aim to evaluate the efficacy of a short-term, home-based, high-intensity
interval (HIT) programme in improving cardiovascular fitness in healthy volunteers aged 55
and above, with an age-comparison to younger individuals taking part in the same training
regime.
It will also explore the efficacy of time-matched 'static' interventions for improving
cardiovascular parameters in middle-aged females and older adults.
Status | Completed |
Enrollment | 48 |
Est. completion date | October 1, 2019 |
Est. primary completion date | October 1, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 55 Years and older |
Eligibility |
Inclusion Criteria: Age > 55 years Able to give informed consent Exclusion Criteria: - Current participation in a formal exercise regime - A BMI < 18 or > 35 kg·m2 - Active cardiovascular disease: - Uncontrolled hypertension (BP > 160/100) - Angina - Heart failure (class III/IV) - Significant arrhythmia - Right to left cardiac shunt - Recent cardiac event - Taking beta-adrenergic blocking agents - Cerebrovascular disease: - Previous stroke - Aneurysm (large vessel or intracranial) - Epilepsy - Respiratory disease including: - Pulmonary hypertension - Significant COPD - Uncontrolled asthma - Malignancy - Metabolic disease e.g. diabetic patients - Clotting dysfunction - Significant Musculoskeletal or neurological disorders - Family history of early (<55y) death from cardiovascular disease |
Country | Name | City | State |
---|---|---|---|
United Kingdom | The University of Nottingham, Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, Royal Derby Hospital | Derby |
Lead Sponsor | Collaborator |
---|---|
University of Nottingham |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in VO2 Max (L/min) assessed by Cardio-pulmonary exercise test (CPET) | To determine the efficacy of bodyweight HIT for improving aerobic fitness | 31 days | |
Secondary | Change in Anaerobic Threshold (L/min) using CPET | To determine the efficacy of bodyweight HIT for improving aerobic fitness | 31 days | |
Secondary | Change in resting glucose and insulin sensitivity (mmol/L) | The effects of HIT on improving glucose control using Oral Glucose Tolerance Test (OGTT) and enzyme-linked immunosorbent assay (ELISA) | 31 days | |
Secondary | Change in muscle architecture as assessed by ultrasound | To assess the effects of HIT on improving muscle structure and function | 31 days | |
Secondary | Change in body composition (fat, muscle, bone (g)) as assessed by Dual-energy Xray Absorptiometry (DEXA) | To assess the effects of HIT on improving muscle structure and function | 31 days | |
Secondary | Feasibility of home HIT assessed using a preset feasibility questionnaire | To assess the feasibility and acceptability of performing a HIT programme at home | 31 days |
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