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High-frequency Jet Ventilation clinical trials

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NCT ID: NCT06285994 Recruiting - Bronchoscopy Clinical Trials

Complications of High Frequency Jet Ventilation

Start date: April 20, 2024
Phase:
Study type: Observational

High frequency jet ventilation (HFJV) has been introduced in 1967 as technique allowing ventilation with simultaneous access to the airway for bronchoscopy. Continuous improvement in the technique has led to a large use during interventional bronchoscopy, especially in large centers. However, complications occuring during the use of HFJV are poorly known. In this retrospective cohort study, the charts of all patients who had a bronchoscopy with the use of HFJV between 2019 and 2023 in our hospital will be analyzed. Primary outcome will the description of all complications during HFJV. Complications are defined as: - Hypoxia: SpO2 < 90% for 1 min - Severe hypoxia: SpO2 < 85% for 1 min - Hemodynamic instability, defined as Arterial pressure < 90/60 - Cardiac arrhythmia - Laryngospasm or bronchospasm - Barotrauma or volutrauma - Need for ICU admission A model predicting the risk for developing any complication will be developped using 2 mathematical methods: - a multivariate analysis - a data mining approach For both approaches, the following variables will be included in the model: - Age - Gender - Weight - Height - BMI - Smoking - Alcohol consumption - Consumption of Other drugs - ASA class - Obstructive pulmonary disease - Restrictive lung disease - COPD status (1, 2, 3, 4) - Interstitial lung disease - Lung tumor - Trachea location - Carina location - Bronchial location - Pulmonary or tracheal stenosis - Presence of stridor - Severe stenosis (< 6 mm) - Baseline SpO2 (pre-intervention) - Pre-intervention oxygen requirement Procedure - Duration (min) - Stent placement - Dilation - Laser treatment - Length of hospital stay Lung function tests - FEV1 (forced expiratory volume) - VC (Vital Capacity) - FEV1/VC (Tiffeneau ratio) - CPT (total lung capacity) - DLCO (carbon monoxide diffusion)

NCT ID: NCT04188613 Completed - Clinical trials for Tracheostomy Complication

Use of High-Frequency Jet Ventilation During Percutaneous Tracheostomy

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Percutaneous tracheostomy is the mouth opening of the tracheal ostium to the skin by creating an opening in the anterior wall of the trachea using Seldinger methods. This procedure is done using an endotracheal tube (ETT) or a laryngeal mask (LMA). High-frequency jet ventilation (HFJV) commonly used in oropharyngeal surgeries and creates an extra passage for the procedure. The investigators aimed to demonstrate the effective use of HFJV in percutaneous tracheostomy.

NCT ID: NCT03378752 Completed - Atelectasis Clinical Trials

Atelectasis Formation Using HFJV During Stereotactic Solid Organ Ablations

Start date: October 2, 2017
Phase:
Study type: Observational

Atelectasis formation using HFJV during stereotactic solid organ ablations. Primary endpoint will be to study the formation of atelectasis during HFJV. Secondary endpoint will be to study liver displacement over time. Reference groups will be found in previous published articles as referred to above. Materials and methods: A radiological protocol has been made for the CT-scanner to take 10 cm volume Scans of the lower part of the lung. The scans will have its' lower border tangential to the top of the diaphragm. The first scan will be performed in the same session as the routine scan of the liver is performed after the patient is anesthetized. These Scans will then be repeated every 15 minute during the first 45 minutes. Arterial bloodgas analysis, transcutaneous CO2, blood pressure, saturation as well as parameters from the jet ventilator and the standard ventilator will be recorded.

NCT ID: NCT02888067 Terminated - Clinical trials for High-Frequency Jet Ventilation

Surgical Conditions During Vocal Cord Surgery Requiring Jet Ventilation With Moderate vs. Deep Neuromuscular Block

Start date: July 1, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether deep neuromuscular blockade provides better surgical conditions than moderate neuromuscular blockade in patients undergoing vocal cord resections requiring jet ventilation.