Clinical Trials Logo
  1. Home
  2. High Flow Nasal Cannula
  3. NCT02958488

Efficacy and Tolerance of High Flow Nasal Cannula for Respiratory Distress Syndrom in Late Preterms (34-36 Weeks) — PRIMAIR  

High Flow Nasal Cannula Clinical Trial

Official title:
Prospective Efficacy and Tolerance Data Collection in 34 to 36 Weeks Preterm Neonates Treated by High Flow Nasal Cannula for Respiratory Distress Syndrom

Clinical Trial Summary

The main objective of the study is to gather preliminary data on the effectiveness of High Flow Nasal canula (HFNC), provided since the delivery room, for ventilatory support in newborns of 34-36 weeks with moderate respiratory distress syndrome (RDS).

The secondary objective is to evaluate the safety of HFNC in this indication.

Clinical Trial Description

Treatment with HFNC will start maximum 30 minutes after birth at an initial flow rate of 2L/Kg/min.

According to retraction signs, flow may be increased by gradual increments of 1L/min to reach a maximum flow rate of 5L/kg/minute.

Patients not improving after 2 hours of support with HFBNC will be hospitalized in the neonatal intensive care unit (NICU), and HFNC maintained as long as necessary, with regular attempts of weaning.

At any moment during the study, aggravation will lead to stop HFNC trial, and the infant management decided by the physician involved in the patient's care.

Aggravation is definined by one of the following conditions: Silverman-Anderson score > 6, and / or FiO2 > 0.5 and / or severe apneas and / or hemodynamic instability. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02958488
Study type Interventional
Source University Hospital, Montpellier
Contact Gilles Cambonie, Professor
Email g-cambonie@chu-montpellier.fr
Status Recruiting
Phase N/A
Start date March 16, 2016
Completion date March 2020
View Details
See also
  Status Clinical Trial Phase
Completed NCT03091504 - Evaluation on the Efficacy of Bronchodilator Nebulization Via High Flow Nasal Cannula N/A
Not yet recruiting NCT04560842 - The Efficacy of High-flow Nasal Cannula Oxygen Therapy in Sepsis Patients N/A
Completed NCT02793674 - HFNC Flow Titration and Effort of Breathing in the PICU N/A
Completed NCT02943863 - Regional Ventilation During High Flow Nasal Cannula and Conventional Nasal Cannula in Patients With Hypoxia N/A
Recruiting NCT05505279 - Ventilatory Effects of THRIVE During EBUS Phase 3
Completed NCT03066934 - A Multicentered Study on Efficiency of Noninvasive Ventilation Procedures
Completed NCT03148262 - High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients N/A
Not yet recruiting NCT04293991 - High Flow Nasal Cannula in Immunocompromised Patient With Acute Respiratory Failure N/A
Recruiting NCT06306651 - High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea N/A
Completed NCT03845244 - Weaning Protocol for High Flow Nasal Cannula Oxygen Therapy N/A
Completed NCT04965844 - Closed-loop Oxygen Control for High Flow Nasal Therapy N/A
Not yet recruiting NCT05467332 - Tracheal Positive Pressure During High Flow Nasal Oxygen Administration in Critically Ill Patients: a Physiologic Study.
Completed NCT04325906 - Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS N/A
Completed NCT03529994 - Work of Breathing and Oxygen Saturation in Infants Receiving High Flow Nasal Cannula (HFNC)