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Hidradenitis clinical trials

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NCT ID: NCT03713632 Completed - Clinical trials for Hidradenitis Suppurativa

Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)

SUNRISE
Start date: February 25, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study was to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week 52 in subjects with moderate to severe HS. Moreover, this study assessed the safety and tolerability of secukinumab.

NCT ID: NCT03713619 Completed - Clinical trials for Hidradenitis Suppurativa

This is a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS).

SUNSHINE
Start date: January 31, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week 52 in subjects with moderate to severe HS. Moreover, this study will also assess the safety and tolerability of secukinumab.

NCT ID: NCT03683238 Completed - Clinical trials for Vitamin D Deficiency

Nutritional Status and Hidradenitis Suppurativa (Acne Inversa)

NutriHidra
Start date: May 2015
Phase:
Study type: Observational

Hidradenitis suppurativa (HS) is a chronic inflammatory, debilitating skin disorder. The exacerbating factors of HS include nutrition and adiposity. The objective of this study was to investigate the relationships between body composition and the adherence to the Mediterranean diet (MD) with the severity of HS in a sample of naïve-treatment patients with HS. In the wake of this evidence, in the study to investigate the relationships between nutritional status, the adherence to the MD, body composition, and the severity of HS in a sample of naïve-treatment patients with HS compared to control group matched for sex, age, and body weight.

NCT ID: NCT03668925 Completed - Clinical trials for Hidradenitis Suppurativa

Association Between Hidradenitis Suppurativa and Spondyloarthritis

VESPA
Start date: May 1, 2013
Phase: N/A
Study type: Interventional

Hidradenitis suppurativa is a chronic dermatosis, characterized by an inflammation of the follicular epithelium in the apocrine glands. The hypothesis of a link between hidradenitis suppurativa and inflammatory rheumatism has been widely considered, with evidence in support of this theory accumulating from several case reports and small series. The most frequently cited rheumatismal disease thought to be associated with Hidradenitis suppurativa is spondyloarthritis. Taken together, these data suggest that there may a link between hidradenitis suppurativa and spondyloarthritis, but literature data are sparse, and to date, no study has investigated or demonstrated such a relation. Indeed, existing studies to date were observational, descriptive, and retrospective, and did not use modern diagnostic approaches for documenting spondyloarthritis, such as magnetic resonance imaging (MRI) or the recent classification of spondyloarthritis.

NCT ID: NCT03628924 Completed - Clinical trials for Hidradenitis Suppurativa

A Study to Evaluate the Efficacy, Safety, and Tolerability of Guselkumab for the Treatment of Participants With Moderate to Severe Hidradenitis Suppurativa (HS)

NOVA
Start date: September 4, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, and tolerability of guselkumab in adult participants with moderate to severe hidradenitis suppurativa (HS).

NCT ID: NCT03607487 Completed - Clinical trials for Hidradenitis Suppurativa

A Placebo-Controlled Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa

Start date: October 15, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety of INCB054707 over an 8-week treatment period in men and women with moderate to severe hidradenitis suppurativa.

NCT ID: NCT03569371 Completed - Clinical trials for Hidradenitis Suppurativa

A Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa

Start date: July 17, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety of INCB054707 in men and women with moderate to severe hidradenitis suppurativa (HS).

NCT ID: NCT03512275 Completed - Clinical trials for Hidradenitis Suppurativa

A Study of Bermekimab in Patients With Hidradenitis Suppurativa

Start date: June 20, 2018
Phase: Phase 2
Study type: Interventional

Phase 2 study of bermekimab in patients with moderate to severe Hidradenitis Suppurativa.

NCT ID: NCT03487276 Completed - Clinical trials for Hidradenitis Suppurativa (HS)

Efficacy and Safety Study of IFX-1 in Patients With Moderate to Severe Hidradenitis Suppurativa (HS)

SHINE
Start date: February 26, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether IFX-1 is safe and effective in the treatment of moderate to severe hidradenitis suppurativa.

NCT ID: NCT03289585 Completed - Clinical trials for Hidradenitis Suppurativa

A National Registry For Patients With Hidradenitis Suppurativa

Start date: August 2015
Phase:
Study type: Observational

The goal of this study is to get a better understanding of the skin condition, Hidradenitis Suppurativa, and to find out how the disease affects quality of life. The investigators hope this information will help improve treatment for this skin condition.