Herpes Zoster Clinical Trial
Official title:
Burden of Herpes Zoster and Post-herpetic Neuralgia Among People ≥ 50 Years Old in France: the POSTHER Study
The purpose of this study is to assess the burden of Herpes zoster (HZ) and post-herpetic neuralgia (PHN) among people ≥ 50 years old in France, in terms of healthcare resources used, medical direct and indirect costs, as well as pain severity and impact on quality of life.
- An observational, prospective cohort study of patients ≥ 50 years old with a Herpes
Zoster (HZ) diagnosis, carried out by a national random sample of community first line
practitioners concerned by HZ diagnosis: general practitioners, dermatologists and
ophthalmologists.
- All patients ≥ 50 years old with a HZ diagnosis (as the primary diagnoses and without
history of previous HZ) during approximately 6 months inclusion period will be included
in the HZ cohort, until total study target is achieved.
- All Patients of the HZ cohort presenting a Post-herpetic neuralgia (PHN) 3 months after
onset of the HZ rash onset will be included secondarily in the PHN cohort
- Patients of the HZ cohort will be followed-up for 3 months (i.e. 1 and 3 months after HZ
rash onset) and patients of the PHN cohort will be followed-up for additional 6 months
(i.e., 6 and 9 months after HZ rash onset) using phone interviews with a nurse.
- 250 cases of HZ and 40 cases of PHN are expected, with the hypothesis of 16% of PHN 3
months after HZ rash onset.
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