Heroin Addiction Clinical Trial
Official title:
Methadone Maintenance Treatment Outcome Study in Taiwan
Opioid abuse is a complex problem, which not only impacts on the affected individuals'
physical and psychological health, but also threatens public security and the productivity
of the society. Further, through needle sharing and sexual contacts, injecting drug users
(IDUs) have become laden with HIV and HIV related health problems, representing a serious
public health threat all over the world. In Taiwan, since the identification of the first
HIV-infected IDU in 1987, the incident cases have continued to increase, reaching a height
of 2,461 in 2005. In order to contain the epidemics of HIV among IDUs, and to prevent its
spread to the population in general, the Center for Disease Control (CDC) collaborated with
the Department of Justice to initiate and implement a number of harm reduction programs in
2005. The fact that opioid addiction is officially treated as a health rather than a legal
issue itself represents a remarkable milestone in Taiwan. Among these harm reduction
programs, including needle and syringe exchange for IDUs as well as substitution treatment
approaches for opioid dependence, methadone maintenance treatment (MMT) perhaps represents
the most most important and most crucial component. Remarkably, in a relatively short time
span, more than 60 MMT programs were established, which enrolled more than 15,000 heroin
addicts. This notwithstanding, the overall and differential effectiveness of these MMT
service delivery systems, as well as the characteristics of these programs and the patients
that might contribute toward treatment response or failure remain largely unknown. Such
knowledge base is crucial for establishing standardized and feasible outcome evaluation
processes for opioid addicts receiving MMT programs, as well as for the further improvement
of the efficacy and effectiveness of these programs, in Taiwan.
In order to address some of these issues, this study adopts a multi-site, prospective
clinical follow-up design. It aims at establishing a research network for examining MMT
outcome, developing standardized MMT outcome assessment instruments and procedures, and
identifying predictors of MMT outcome. The findings may contribute to the better
understanding of the characteristics of opioid addicts, the effectiveness of MMT and
remaining service needs for opioid addicts in Taiwan.
n/a
Observational Model: Case-Only, Time Perspective: Prospective
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