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Small Versus Large Bite Closure of Emergency Midline Laparotomy — E-STITCH  

Hernia, Ventral Clinical Trial

Official title:
A Randomized Controlled Trial on Small Versus Large Bite Closure of Emergency Midline Laparotomy

Clinical Trial Summary

In daily practice, midline laparotomy is an incision frequently performed by surgeons to achieve a rapid and wide access to the abdomen. However, incisional hernia stands as the most common complication following this type of incision, with an incidence reaching up to 20% and even higher in the case of emergency laparotomy.

A recent randomized controlled trial compared small bite sutures and large bite closure of elective midline laparotomy and reported a significant decrease of incisional hernia rate from 18% to 5.6% in favor of small-bite technique. These promising results were subsequently confirmed in a wide-scale multicenter double-blinded randomized trial, the STITCH study.

The investigators will conduct this randomized controlled trial to compare the small tissue bite (SB) technique and the large bite (LB) technique for closure of emergency midline laparotomy. The main outcome of the study will be the incidence of incisional hernia within one year after surgery.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04098380
Study type Interventional
Source Mansoura University
Contact Sameh Emile, M.D.
Phone 201006767150
Email sameh200@hotmail.com
Status Recruiting
Phase N/A
Start date September 21, 2019
Completion date December 30, 2021
View Details
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