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Hernia, Ventral clinical trials

View clinical trials related to Hernia, Ventral.

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NCT ID: NCT01280370 Completed - Clinical trials for Incisional Hernia Repair

Prospective Evaluation of Laparoscopic and Open Incisional Hernia Repair: a Multicenter Cohort Study

IHR_SALTC
Start date: September 2010
Phase:
Study type: Observational

Nowadays incisional hernia are primarily repaired using prosthetic meshes. In Switzerland such meshes are mainly implanted via open or laparoscopic approach. The differential impact of these two types of surgical technique on recurrence rate will be investigated with this study. With this multicenter cohort study the outcomes of laparoscopic and open incisional hernia repair will be investigated prospectively. Hernia recurrence is the main outcome measure. Hypothesis: Laparoscopic incisional hernia repair is associated with a lower recurrence rate compared to open incisional hernia repair.

NCT ID: NCT01205399 Completed - Hernia Clinical Trials

A Retrospective Study With Prospective Follow-Up of Complex Ventral Hernia Repair Utilizing the AlloMax Surgical Graft

AlloMax
Start date: September 2010
Phase: N/A
Study type: Observational

This study will enroll subjects who underwent a ventral hernia repair using the AlloMax Surgical Graft at least 9 months in the past. All subjects who underwent a ventral hernia repair using the AlloMax Surgical Graft at least 9 months in the past will be contacted and asked to take part in this clinical study. The consented subjects' medical records will be reviewed for evidence of any risk factors of hernia recurrence, procedure time, complications and any documented recurrences. The subjects will be asked to undergo a physical exam to rule out any recurrences that were not documented in the medical records.

NCT ID: NCT01183325 Completed - Ventral Hernias Clinical Trials

Prospective Evaluation of the Proceed Ventral Patch With and Without Laparoscopic Evaluation

Start date: September 2009
Phase: N/A
Study type: Interventional

For small (2-3cm) ventral and umbilical hernias the discussion for primary suture repair or the use of mesh continues. About 5 years ago the Ventralex patch was introduced, which combines a layer of PTFE mesh with a small polypropylene mesh and includes a circular memory ring. Despite the elegance of using this patch, recent experience showed several drawbacks both in design and efficacy (3). With the recent development of the Proceed Ventral Patch (PVP), new elements have been introduced to overcome some of these issues. The aim of this study is to evaluate the efficacy of clinical placement of the PVP in the intra-abdominal position in the treatment of small ventral hernias.

NCT ID: NCT01162564 Completed - Ventral Hernia Clinical Trials

Flexible Composite Next Generation Tissue Separating Mesh in Laparoscopic Incisional/Ventral Hernia Repair

Start date: June 2010
Phase: N/A
Study type: Observational

This is a multi-center, observational study of incisional/ventral hernia repair with NG-TSM laparoscopically. The study is not randomized and has a single treatment design assessing NG-TSM intra-operatively, its ease of use and handling characteristics.

NCT ID: NCT01115400 Completed - Hernia Clinical Trials

Quality of Life Evaluations in Patients With Abdominal Wall Hernias

QOL
Start date: July 2007
Phase:
Study type: Observational

The aim of this study is to evaluate the quality of life in patients with abdominal wall hernias using a user-friendly survey that is designed specifically for this population of patients. The investigators would like to use this survey to elucidate how quality of life of the patient is changed with the presence of an abdominal wall hernia.

NCT ID: NCT01109771 Completed - Ventral Hernia Clinical Trials

Absorbable Versus Permanent Mesh Fixation Trial in Laparoscopic Midline Ventral Hernia Repair

SORBET
Start date: April 2010
Phase: Phase 4
Study type: Interventional

To compare the use of absorbable tackers versus permanent tack fixation using a polyester large pore mesh in laparoscopic midline ventral hernia repair in a multicenter (Belgian) prospective randomized single-blinded trial. All patients referred for elective midline ventral hernia repair should be assessed for eligibility and entered in a study log, detailing all included patients during the study period.

NCT ID: NCT01060046 Completed - Ventral Hernia Clinical Trials

Analysis and Characterization of Biologic Implants

Start date: August 2007
Phase:
Study type: Observational

The purpose of this study is to investigate what happens to biologic mesh in the body over time on a molecular level. To date, it is not known what agents, enzymes, or proteins are interacting at the implantation site that contributes to mesh remodeling and/or degradation. Investigators on this project will identify patients with previously placed mesh who are needing reoperation on the same site and take a biopsy of the mesh during the normal course of surgery. Basic data surrounding the surgical procedure will be collected. The mesh samples will be analyzed for enzymes and proteins and examined histologically for processes that signify remodeling and/or degradation. Control patients will undergo biopsy of abdominal fascia at laparoscopic trocar sites in a manner that will not affect the outcome(s) of their procedure or other risk to the incision site.

NCT ID: NCT00908193 Completed - Clinical trials for Abdominal Wall Hernia

Laparoscopic "DA VINCI" Robot Assisted Abdominal Wall Hernia Repair

ARTE
Start date: July 2007
Phase: Phase 4
Study type: Interventional

The aim of this study is to prove the superiority of the robotic assistance in laparoscopic repair of abdominal wall hernias . In this monocentric randomized controlled trial, the use of the DA VINCI robot might reduce the post-operative pain of the patient resulting in a 40% reduction of morphine consumption.

NCT ID: NCT00894582 Completed - Ventral Hernia Clinical Trials

Prospective Study of Ventral Hernia Repair

Start date: January 2007
Phase: N/A
Study type: Observational

Immediate post-operative abdominal compartment syndrome is a feared complication after hernia repair in patients with a "loss of abdominal domain." Replacement of the viscera within an unyielding stiff abdominal wall may compromise the perfusion of the intestines, elevate the diaphragm, and interfere with ventilation. The components separation technique, used to repair these massive hernias, employs bilateral relaxing incisions in the external oblique muscle and fascia in order to approximate the rectus abdominis muscles in the midline. Reducing a large volume hernia into the abdominal cavity and primary closure of the abdominal wall should cause problems both with abdominal compartment pressure and with postoperative ventilation, but in the investigators' 13-year experience with over 250 cases, this has not been seen clinically, and the investigators sought to understand why. The investigators' hypothesis is that releasing the rectus muscles from the external obliques expands the intra-abdominal compartment, reclaims lost domain, and thus reduces abdominal pressure and respiratory problems. The investigators have previously reported increased abdominal volumes using the components separation technique in a retrospective series, but patients were not standardized for the collection of data, and no pulmonary function tests were obtained in that series (Hadad, in press). The purpose of this study was to prospectively analyze the effect of this surgical technique on abdominal volume and pulmonary function.

NCT ID: NCT00866814 Completed - Ventral Hernia Clinical Trials

Study Of Hernia Repair Utilizing The Bard Ventrio Hernia Patch

Start date: March 2009
Phase: N/A
Study type: Observational

This study will collect data on patients undergoing hernia repair using the Bard Ventrio Hernia Patch. The study will evaluate hernia recurrence rates, operating time, quality of life and complications associated with the device and surgical procedure.