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Hernia, Inguinal clinical trials

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NCT ID: NCT03591146 Completed - Inguinal Hernia Clinical Trials

Phase I/II Dose-escalation Study to Evaluate Safety, PK and Efficacy of TLC590 for Postsurgical Pain Management

Start date: July 31, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I/II, randomized, double-blind, comparator-controlled, dose-escalation study to assess the safety, PK, and efficacy of single postsurgical application of TLC590 compared with Naropin®

NCT ID: NCT03590145 Completed - Inguinal Hernia Clinical Trials

Reliability of the Doha Agreement Classification of Groin Pain

Start date: October 25, 2017
Phase:
Study type: Observational

This study will investigate the reproducibility of a clinical diagnostic classification system for groin pain between two different examiners.

NCT ID: NCT03566784 Completed - Inguinal Hernia Clinical Trials

Electrocoagulation Employment During TAPP Inguinal Hernia Repair

Start date: June 1, 2018
Phase:
Study type: Observational

Laparoscopic TAPP (transabdominal preperitoneal) hernia repair presents a minimally invasive surgical procedure, which tends to be a gold standard in a wide range of inguinal hernia operations. Postoperative neuralgia is a troublesome complication following TAPP, which occurs in 0.2-7% of patients. The most common cause of nerve injury is an inappropriate use of electrocoagulation or dangerous tissue dissection during TAPP. However, the association between electrocoagulation employment during TAPP and postoperative neuralgia has not been investigated properly until now. The aim of the project is to compare postoperative pain (postoperative neuralgia) in patients undergoing TAPP inguinal hernia repair with/without the use of electrocoagulation.

NCT ID: NCT03566433 Completed - Inguinal Hernia Clinical Trials

Postoperative Pain After Endoscopic TEP vs. Lichtenstein Hernioplasty in Inguinal Hernia Repair

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Immediate pain reaction and return to work after TEP or Lichtenstein hernia repair have not been studied. In this multicenter trial the patients are allocated to surgery using TEP (n=50) or Lichtenstein (n=50) technique. Pain and return to work are recorded postoperatively up to one month. Immediate and late complications are also analyzed.

NCT ID: NCT03563092 Completed - Clinical trials for Inguinal Hernia Without Obstruction or Gangrene

Closed Suction Drain vs no Drain on Symptomatic Seroma Formation After Laparoscopic Inguinal Hernia Repair

SALHS
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The current study aims to determine whether a use of closed suction drain following laparoscopic inguinal hernia surgery performed for an inguinoscrotal variety can decrease the incidence of symptomatic seroma formation requiring interventions and thus, prevent postoperative morbidity.

NCT ID: NCT03558555 Completed - Inguinal Hernia Clinical Trials

Determine the Clinical Advantage of IV vs PO Acetaminophen

Start date: December 8, 2017
Phase: Phase 4
Study type: Interventional

There is limited research on the clinical outcome differences between intravenous (IV) acetaminophen versus oral (PO) acetaminophen. With the costs of intravenous acetaminophen sometimes being almost 100 times the cost of PO acetaminophen, it is not only important fiscally but also clinically to differentiate the benefits of IV vs PO acetaminophen. The proposed research study is to determine the clinical advantages of IV vs PO acetaminophen during the post-operative recovery time for ambulatory surgery patients by analyzing differences in time to first opioid delivery, pain scores, and patient satisfaction.

NCT ID: NCT03526731 Completed - Postoperative Pain Clinical Trials

Analgesic Efficacy of Trans-muscular Quadratus Lumborum Block After Unilateral Inguinal Hernia Repair

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

A significant component of pain experienced after abdominal surgery is related to incision of the abdominal wall and adequate analgesia can be a challenge. The ultrasound-guided (USG) quadratus lumborum block QLB was first described by Rafael Blanco in a presentation at ESRA 2007 at the XXVI Annual ESRA Congress in Valencia, Spain. Blanco described a potential space posterior to the abdominal wall muscles and lateral to the quadratus lumborum muscle where Local anesthetics can be injected. This technique provide analgesia after abdominal surgery due to spread of LA from its lumbar deposition cranially into the thoracic paravertebral space where lateral and anterior cutaneous branches from Th7 to L1 can be blocked . This was proved by Carney et al. who found traces of contrast agent in the TPVS following application of this block A novel USG QL block is the transmuscular approach which relies on clearly identifiable sonographic bony landmarks, Where the needle is advanced through the QL muscle, penetrating the ventral proper fascia of the QL muscle and LA is finally injected between the QL and Psoas major (PM) muscle. The transmuscular QL block does not result in redundant antero-lateral spread of the injectate. This may indicate that lower volumes of LA potentially can be used and yet provide extensive thoracolumbar anesthesia. This study was designed to compare the duration of analgesia provided by the original QLB and transmuscular QLB in patients undergoing surgical repair of unilateral inguinal hernia.

NCT ID: NCT03526341 Completed - Inguinal Hernia Clinical Trials

Post Market Clinical Follow Up Study for ReliaTackā„¢ Articulating Reloadable Fixation Device With Deep Purchase Tacks

RAFDT
Start date: April 25, 2018
Phase:
Study type: Observational

A post-market clinical follow-up study for ReliaTackā„¢ articulating reloadable fixation device with deep purchase tacks

NCT ID: NCT03520907 Completed - Postoperative Pain Clinical Trials

The Comparison of the Transversalis Fascia Plane Block With Ilioinguinal/Iliohypogastric Nerve Block

Start date: April 26, 2018
Phase: N/A
Study type: Interventional

This study compares the transversalis fascia plane block with the ilioinguinal/iliohypogastric nerve block in children undergoing hernia repair surgery. Half of participants will receive the transversalis fascia plane block, while the other will receive the ilioinguinal/iliohypogastric nerve block.

NCT ID: NCT03515434 Completed - Postoperative Pain Clinical Trials

Comparison of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Inguinal Hernia Repair

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Multimodal analgesia is used to control postoperative pain in inguinal hernia repair. Transversus abdominis plane block is an effective regional anesthesia technique for postoperative analgesia in inguinal hernia repairs. The erector spinae plane block applied to thelow thoracic region was also reported to provide effective analgesia in these surgeries. In this study, we aimed to determine and compare the effects of transversus abdominis plane block and lumbar erector spinae plane block on postoperative pain in inguinal hernia repairs.