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Hernia, Inguinal clinical trials

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NCT ID: NCT01592942 Recruiting - Inguinal Hernia Clinical Trials

Mesh Fixation in Lichtenstein Hernioplasty

Start date: August 2012
Phase: N/A
Study type: Interventional

This is a prospective, randomized multi-centre study to find out most safe, feasible, painless and cost-effective mesh fixation method in inguinal hernia operation. Three mesh fixation techniques are compared to find out best technique in local anaesthesia Lichtenstein operation. Our hypothesis is that glue fixation is safe, simple and cheap method compared to conventional Lichtenstein technique.

NCT ID: NCT01591395 Recruiting - Inguinal Hernia Clinical Trials

Prospective Randomized Trial Comparing Three-port and Single-port TEP Repair in Adults

Start date: August 2010
Phase: N/A
Study type: Interventional

Inguinal hernia is one of the most common surgical diseases. Over the past years, the safety and feasibility of laparoscopy was established and gaining popularity in recent few years. Laparoscopic inguinal hernia repair was associated with less post operative pain, a shorter recovery period, earlier return to normal daily activities and work, and better cosmetic results. The laparoscopic hernia repair usually require three working ports ranging from 5 to 10 mm. However, with each increasing laparoscopic ports usually associated with possible increasing morbidity and pain related to ports. Efforts are continuing to further reduce the port related morbidities and improve the cosmetic outcomes of laparoscopic surgery, including reduction of the size and number of ports. This has led to the evolution of a novel surgical approach now collectively known as laparoendoscopic single site surgery. LESS has been performed for variable indications including extirpative and reconstructive urologic procedure via the transperitoneal approach. Early experience has demonstrated the feasibility as well as the safe and successful completion of these LESS procedures. Although these initial reports are promising, the clinical advantages of LESS procedures over conventional laparoscopic procedures have not been defined. Therefore, we conducted a single center, randomized trial to compare the safety and other outcomes after conventional laparoscopic and LESS inguinal hernia repair in adult patients.

NCT ID: NCT01590940 Recruiting - Clinical trials for Evaluate the Use of a New Mesh Type in Open Inguinal Hernia Repair

Use of Parietex Plug and Patch Hernia System in Open Inguinal Hernia Repair

Start date: April 2012
Phase: N/A
Study type: Observational

The use of synthetic mesh plugs for open inguinal hernia repair has seen dramatic variability in the number and composition of meshes currently on the world market. The use of biomaterials (PLLA, PGA) in hernia mesh is a relatively new and innovative method. These selected polymers have the ability to degrade while implanted, allowing for sufficient natural tissue healing and scarring. This usage presumably favors a decrease in foreignness, inflammatory reaction, recurrence, and incidence of chronic groin pain. Prior studies with similar plug meshes in the same indication have yielded favorable results which require this mesh to be investigated in its specific application. Primary Objective Evaluate the incidence of peri-operative and post-operative complications after the application of the Parietex plug and patch hernia system in open inguinal hernia repair. We will assess the efficacy of this mesh by examination and the application of a pain scale at the following intervals: 1 month, 3 months, and 1 year, respectively. Assessment is intended to evaluate: - Patient report of pain via their Pain score - Wound complication - Incidence of chronic groin pain - Recurrence rate - Other complications Secondary Objectives Record the description and assessment of the Parietex plug and patch hernia system: - surgical technique - description of dissection and mesh placement - method of fixation - operative times, anesthesia choice - length of hospital stay - mesh handling characteristics - return to daily activities - overall patient satisfaction

NCT ID: NCT01589796 Recruiting - Adult Clinical Trials

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

Start date: April 2012
Phase: N/A
Study type: Interventional

Pain relief after open inguinal hernia repair could be improved by administration of TAP block or ilioinguinal/iliohypogastric nerve block. It is unclear which one works better. The investigators hypothesize that doing TAP block closer to the middle of the abdomen would result in improved pain relief due to simultaneous block of ilioinguinal/iliohypogastric nerves.

NCT ID: NCT01450345 Recruiting - Postoperative Pain Clinical Trials

Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The study carry out is to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy, opiod sparing, adverse effect and clinical value in post-operative pain management.

NCT ID: NCT01391455 Recruiting - Inguinal Hernia Clinical Trials

Isolation of the Spermatic Cord in Mesh Inguinal Hernia Repair

Start date: July 2011
Phase: N/A
Study type: Interventional

There are in excess of 1 million operations performed annually to repair inguinal hernias, mostly in the male population. Unfortunately, some patients continue to suffer both groin or testicular pain for varying lengths of time postoperatively. This can lead to a severe degradation of the patient's lifestyle, work habits and sexual function. The origin of the pain is felt to be secondary to the inflammatory reaction caused by the mesh. This also involves the spermatic cord and its structures, leading to orchidinia and possibly azospermia.

NCT ID: NCT01348477 Recruiting - Inguinal Hernia Clinical Trials

Comparison Between Elliptical Domed Mesh Technique and Lichtenstein Technique in Inguinal Hernia

Start date: October 2010
Phase: N/A
Study type: Interventional

The investigators describe a new surgical technique for inguinal hernia open repair, which will be compared with the Lichtenstein technique. The investigators seek to find the difference between the two techniques in postoperative pain.

NCT ID: NCT01326039 Recruiting - Inguinal Hernia Clinical Trials

Ultrasound-guided Ilioinguinal-iliohypogastric Block for Inguinal Hernia Repair

Start date: May 2010
Phase: Phase 4
Study type: Interventional

Aim: To investigate whether ultrasound-guided perineural administration of 20 ml bupivacaine 5 mg/ml vs 20 ml isotonic saline at the ilioinguinal-iliohypogastric nerves have a clinically analgesic effect after unilateral open inguinal hernia repair.

NCT ID: NCT01090284 Recruiting - Inguinal Hernia Clinical Trials

The Immunologic Reaction to Polypropylene Mesh in Inguinal Hernioplasty

Start date: March 2010
Phase: N/A
Study type: Observational

The notable development and diffusion of prosthetic surgery of the abdominal wall over the last few years has led to the introduction of light weight meshes. The efficacy of inguinal hernia repair with light weight prosthesis, as well as the better or worse biotolerability with respect to those of light weight, remains questionable in literature, where a clear answer still remains to be given. If there exists a connection between the quantity of material implanted, the immunological reaction to the mesh, the induced oxidative stress and the degree of cicatrization, and consequently the long-term result of the efficacy of the operation, remains to be demonstrated. There are few studies on the immunological reaction to polypropylene meshes, and none on the oxidative stress induced by the mesh. Moreover, only one study has been published that clearly correlates the immunological reaction to the amount of prosthetic material, but was carried out on only a few patients. The aim of this research is to show if there is a relationship between the amount of prosthetic material used and immunological reactions as well as postoperative oxidative stress, and thus to evaluate, if present, the differences in the biological reaction and biotolerability between light-weight and heavy-weight meshes on a statistically significant number of patients.

NCT ID: NCT01090219 Recruiting - Inguinal Hernias Clinical Trials

Polypropylene Meshes in Hernia Repair

Start date: February 2008
Phase: N/A
Study type: Interventional

The aim of this study was to analyze the shrinkage of two different screens in the repair of inguinal hernias in men . 32 patients with unilateral inguinal hernia were assigned randomly. A Lichtenstein tension-free hernia repair was accomplished by emplacing heavy weight versus ultralight weight polypropylene meshes for repair of incisional hernia, marked next to the lips with six titanium clips (LT200).