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Cell-based Non-invasive Prenatal Testing as an Alternative to Invasive Chorionic Villus Sampling

Hereditary Diseases Clinical Trial

Official title:
Cell-based Non-invasive Prenatal Testing - Evaluation of Time of Blood Sampling and Whole Genome Amplification Prior to Genetic Testing

Clinical Trial Summary

The study aims to evaluate cell-based non-invasive prenatal testing (cbNIPT) as an alternative to invasive chorionic villus sampling (CVS) in patients who achieve pregnancy following preimplantation genetic testing for hereditary disorders.

Clinical Trial Description

The study has three main objects: 1. to evaluate the optimal time of blood sampling (gestational week 7-8 or 11-14) 2. to evaluate whole genome amplification prior to genetic analysis og isolated fetal cells (only relevant for monogenic disorders) 3. evaluating specificity and sensitivity ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05453474
Study type Interventional
Source Aalborg University Hospital
Contact
Status Completed
Phase N/A
Start date August 8, 2021
Completion date June 27, 2023
View Details
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