Hereditary Ataxia Clinical Trial
Official title:
Phase I/II Study of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Hereditary Ataxia
The Hereditary Ataxias are a group of genetic disorders characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements. Current treatments for Hereditary Ataxias are mainly pharmacological, rehabilitative, or psychological treatments,while no effective treatment available. Stem Cell therapy is a novel and promising therapeutic strategy for Hereditary Ataxias treatment. In this study, the safety and efficacy of Human Umbilical Cord Mesenchymal Stem Cells transplantation will be evaluated in patients with Hereditary Ataxias.
This Study is designed to evaluate the the safety and efficacy of Human Umbilical Cord Mesenchymal Stem Cells transplantation in patients with Hereditary Ataxias. ;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00004306 -
Clinical and Molecular Correlations in Spinocerebellar Ataxia Type 10 (SCA10)
|
N/A | |
Completed |
NCT04750850 -
Core Stability Exercises and Hereditary Ataxia
|
N/A | |
Active, not recruiting |
NCT06152133 -
Telerehabilitation, Core Stability Exercises and Hereditary Ataxia (TRCore-ataxia)
|
N/A | |
Recruiting |
NCT05160883 -
Neuroimaging Changes in Hereditary Ataxia
|
||
Recruiting |
NCT05160870 -
Genotype-phenotype Correlation and Pathogenic Mechanism in Hereditary Ataxia
|
||
Completed |
NCT00202397 -
Effect of Riluzole as a Symptomatic Approach in Patients With Chronic Cerebellar Ataxia
|
Phase 2 |