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HER-2 Gene Amplification clinical trials

View clinical trials related to HER-2 Gene Amplification.

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NCT ID: NCT04650451 Suspended - Solid Tumor, Adult Clinical Trials

Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors

Start date: December 7, 2020
Phase: Phase 1
Study type: Interventional

This is a Phase 1/2, open-label, multicenter, non-randomized study to investigate the safety, tolerability, and clinical activity of HER2-specific dual-switch CAR-T cells, BPX-603, administered with rimiducid to subjects with previously treated, locally advanced or metastatic solid tumors which are HER2 amplified/overexpressed.