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Efficacy of Pentoxifylline and Rifaximin Combination in Pentoxifylline Refractory Clinical and Subclinical Hepatopulmonary Syndrome

Hepatopulmonary Syndrome Clinical Trial

Clinical Trial Summary

- The study will be a prospective open labelled double blinded randomized controlled study.

- The study will be conducted on patients admitted to Department of Hepatology from 2012 to 2014 at Institute of Liver and Biliary Sciences, New Delhi

- Patients diagnosed as having clinical or subclinical hepatopulmonary syndrome will be started on oral pentoxifylline therapy 400 mg thrice daily for 12 weeks.

- Patients not responding to this therapy will be given divided into 2 arms with one arm receiving additional Tab Rifaximin 400 mg thrice daily or placebo for 12 weeks.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01676597
Study type Interventional
Source Institute of Liver and Biliary Sciences, India
Contact Dr Naveen Kumar, MD
Phone 011-46300000
Email naveenilbsdelhi@gmail.com
Status Recruiting
Phase N/A
Start date September 2012
Completion date September 2014
View Details
See also
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