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Clinical Trial Summary

The purpose of the study is to compare the efficacy, safety and recurrence rate of two therapeutic strategies with ribavirin in patients with chronic hepatitis E and severe acute hepatitis E: fixed duration of treatment for 12 weeks vs variable duration depending on the viremia within 4 weeks of the start of treatment (12 vs 24 weeks).

The purpose of the study is also improve the safety of treatment with Ribavirin by optimizing dose adjusted to renal function, plasma levels of drug and hemoglobin.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02558114
Study type Interventional
Source Hospital Universitari Vall d'Hebron Research Institute
Contact
Status Terminated
Phase Phase 4
Start date December 2015
Completion date November 2018

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