Hepatitis C Virus Clinical Trial
Official title:
An Open-Label Re-Treatment Study With PegInterferon Alfa-2a, Ribavirin and BMS-790052 With or Without BMS-650032 for Subjects With Chronic Hepatitis C
The purpose of this study is to provide anti-HCV drugs to +/- 200 subjects treated in prior BMS studies with placebo + Peginterferon Alfa-2a and Ribavirin and determine if the addition of these drugs can result in higher cure rates in patients who previously failed therapy. Approximately 100 genotype 1b subjects rolling over from BMS study AI447-028 who received placebo will be treated with active drugs in this study.
- Intervention Model:
- Parallel: for all subjects entering the trial
- Cross-over: for genotype 1b subjects rolling over from AI447-028 who require
rescue therapy after initial treatment in this study
- Peginterferon Alfa-2a (pegIFNα-2a)
- Ribavirin (RBV)
- Daclatasvir (DCV)
- Asunaprevir (ASV)
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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