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Benefit of DAA Therapy in HCV Monoinfected and HIV-HCV Coinfected Patients With Mixed Cryoglobulinemia

Hepatitis C, Chronic Clinical Trial

Official title:
Benefit of Direct-acting Antiviral Therapy in Hepatitis C Virus (HCV) Monoinfected and HIV-HCV Coinfected Patients With Mixed Cryoglobulinemia

Clinical Trial Summary

Mixed cryoglobulinemia (MC) is common in patients with chronic hepatitis C virus (HCV) infection. Direct-acting antiviral (DAA) regimens are today very effective with sustained virological response rates (SVR12) above 90%. The objective of this study was to investigate the impact of DAA therapy on cryoglobulin clearance in patients with HCV-associated MC.

Clinical Trial Description

We focused on HCV patients with or without HIV with MC who had at least one cryoglobulin level assessment before and after DAA therapy and investigated the impact of DAA therapy on cryoglobulin clearance. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03342261
Study type Observational
Source Hospices Civils de Lyon
Contact
Status Completed
Phase N/A
Start date March 1, 2017
Completion date November 1, 2017
View Details
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