Hepatitis B Clinical Trial
Official title:
Increasing Hepatitis B Screening Among Korean Church Attendees (Component Project) Program Project Title: Liver Cancer Control Interventions for Asian Americans
The purpose of this study is to design an intervention to increase hepatitis B (HBV)
screening among Korean Americans.
The investigators will design a culturally specific intervention (educational sessions) and
test the effect of the intervention on 1200 Korean Americans.
All subjects will be interviewed before the intervention/control sessions and 6 months after
the sessions to assess HBV screening levels in the two groups. Self-reported HBV screening
will be verified by a review of subjects' medical records.
The primary study hypothesis is that the intervention group will have a higher rate of HBV
serologic testing at follow-up compared to the control group.
The purpose of this study is to design an intervention to increase hepatitis B (HBV)
screening among Korean Americans.
The investigators will design a culturally specific intervention; an educational small group
discussion led by a trained Korean leader. The effect of the intervention will be tested on
1200 Korean Americans.
Subjects will be recruited at Korean churches and invited to join a one-hour discussion of
health issues with other members of their church. One half of the subjects will participate
in the intervention group. These subjects will discuss HBV and will receive resources
related to HBV and where to obtain screening. The other half of the subjects will
participate in the control group. These subjects will discuss nutrition and physical
activity and will receive resources related to these topics, but not related to HBV and
where to obtain screening.
All subjects will be interviewed before the sessions and 6 months after the sessions to
assess HBV screening levels in the two groups. Self-reported HBV screening will be verified
by a review of subjects' medical records.
The primary study hypothesis is that the intervention group will have a higher rate of HBV
serologic testing at follow-up compared to the control group.
Secondary hypotheses are:
The intervention group will have a higher level of knowledge of hepatitis B and liver cancer
at follow-up compared to the control group.
The effect of the intervention on hepatitis B serologic testing will be mediated by
knowledge of hepatitis B and liver cancer.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Screening
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01182311 -
Duration of Long-term Immunity After Hepatitis B Virus Immunization
|
||
| Completed |
NCT04971928 -
Phase 1 Study of GSK3228836 Pharmacokinetics in Participants With Hepatic Impairment
|
Phase 1 | |
| Completed |
NCT03285620 -
A Study of AL-034 to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses in Healthy Participants
|
Phase 1 | |
| Completed |
NCT01884415 -
Phase III, Study to Evaluate the Efficacy of Two Different HBV Vaccination Schemes in Patients With Hepatic Cirrhosis
|
Phase 3 | |
| Recruiting |
NCT05404919 -
Utilization of Hepatitis B Virus NAT+ Donors for Hepatitis B Vaccinated Lung Transplant Candidates
|
Phase 2 | |
| Completed |
NCT02153320 -
Study to Evaluate the Persistence of the Cellular and Humoral Immune Response Following Vaccinations With GlaxoSmithKline (GSK) Biologicals' Candidate Vaccines Containing HBsAg and Different Adjuvants in Healthy Adult Volunteers
|
Phase 1 | |
| Completed |
NCT00352963 -
Immunogenicity & Safety Study of Combined/Separate Vaccine(s) Against Common Diseases in Infants (2,4,6 Months of Age).
|
Phase 3 | |
| Completed |
NCT03567382 -
Arresting Vertical Transmission of Hepatitis B Virus
|
Phase 4 | |
| Not yet recruiting |
NCT04056728 -
A Phase IV Study to Assess the Safety of EupentaTM Inj
|
Phase 4 | |
| Not yet recruiting |
NCT03604016 -
Study to Assess Efficacy of Besifovir and L-carnitine in Chronic Hepatitis B Patients With Nonalcoholic Fatty Liver
|
Phase 4 | |
| Completed |
NCT00753649 -
Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants
|
Phase 4 | |
| Recruiting |
NCT03027258 -
Point-of-Delivery Prenatal Test Results Through mHealth to Improve Birth Outcome
|
N/A | |
| Terminated |
NCT02604199 -
A Multi-dose Study of ARC-520 in Patients With Hepatitis B 'e' Antigen (HBeAg) Negative, Chronic Hepatitis B Virus (HBV) Infection
|
Phase 2 | |
| Completed |
NCT02540538 -
Safety and Immunogenicity of HBAI20 Hepatitis B Vaccine in Naive Adults and Non-responders
|
Phase 1 | |
| Completed |
NCT02421666 -
A Comparative Trial of Improving Care for Underserved Asian Americans Infected With HBV
|
N/A | |
| Completed |
NCT02169674 -
Hepatitis B Booster Study in Adolescence
|
Phase 4 | |
| Completed |
NCT01917357 -
A Comparison of the Immunogenicity and Safety of Quinvaxem in Mono-dose Vials and Uniject
|
Phase 3 | |
| Completed |
NCT01732354 -
Study for Consolidation Period of Chronic Hepatitis B
|
||
| Completed |
NCT01368497 -
Entecavir/Pegylated Interferon in Immune Tolerant Children With Chronic Hepatitis B Virus (HBV) Infection
|
Phase 3 | |
| Recruiting |
NCT01462981 -
Cohort of Hepatitis B Research of Amsterdam
|
N/A |