Hepatitis B Clinical Trial
Official title:
Evaluate the Persistence of Immune Response of GSK Biologicals' Twinrix™ Vaccine, Administered According to a 0,6 Month Schedule and a 0,1,6 Month Schedule, in Healthy Children Aged Between 1-11 Years at the Time of First Vaccine Dose
To evaluate the persistence of anti-hepatitis A virus (HAV) and anti-hepatitis B surface
antigen (HBs) antibodies up to 2, 3, 4 and 5 years after administration of the first dose of
the study vaccine.
The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep
2007.
Open, randomised, self-contained, multicentric, multinational, long-term antibody persistence studies. Immune persistence was compared between subjects who received either two dose or three doses of GSK Biologicals combined hepatitis A and hepatitis B vaccine. The long-term follow-up studies involved taking blood samples at approximately 2, 3, 4 and 5 years after the primary vaccination of combined hepatitis A and B vaccine to assess antibody persistence. No additional subjects will be recruited during the long term follow-up period. ;
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