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Hepatitis B clinical trials

View clinical trials related to Hepatitis B.

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NCT ID: NCT04113915 Not yet recruiting - Viral Hepatitis Clinical Trials

Viral Hepatitis B and C Infection in Patients With Idiopathic Thrombocytopenic Purpura Treated With Triple Therapy

Start date: November 2019
Phase:
Study type: Observational

Aim of the work To estimate frequency of viral HB & C infection in ITP patients who received triple therapy in comparison with another group treated with steroids only. To explore risk factors and routes of transmission of viral HB & C infection in ITP patients who received triple therapy and the another group treated with steroids . - To assess preventive measures of viral HB& C infection in the hematology ward To investigate the influence of viral HB & C infection on clinical picture, response to treatment and side effects in ITP patients who received triple therapy or steroids.

NCT ID: NCT04073459 Not yet recruiting - Hepatitis B Clinical Trials

Safety and Immunogenicity of Hexavalent Vaccine(DTwP-HepB-IPV-Hib) in Healthy Infants

Start date: November 2019
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate immunogenicity and safety of three different doses of candidate hexvalent vaccine in comparison to co-administration of EupentaTM Inj. and Imovax® Polio in separate injections at four weeks after completion of three-dose primary series at 6-10-14 weeks of age when administered to healthy infants and thereby to select the optimal dose of candidate vaccine

NCT ID: NCT04056728 Not yet recruiting - Hepatitis B Clinical Trials

A Phase IV Study to Assess the Safety of EupentaTM Inj

Start date: September 23, 2019
Phase: Phase 4
Study type: Interventional

A prospective, open-label, interventional phase IV study to assess the safety of EupentaTM Inj.{fully liquid pentavalent vaccine, Adsorbed Diphtheria-Tetanus-whole-cell Pertussis-Hepatitis B (rDNA [recombinant-deoxyribonucleic acid])-Haemophilus influenzae type b conjugate vaccine}

NCT ID: NCT04032392 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Immunotherapy of Advanced Hepatitis B Related Hepatocellular Carcinoma With γδT Cells

Start date: July 23, 2019
Phase: Phase 1
Study type: Interventional

To evaluate the safety, tolerability and efficacy of autologous γδT cells in the treatment of advanced hepatitis B-related hepatocellular carcinoma.

NCT ID: NCT03962881 Not yet recruiting - Hepatitis B Vaccine Clinical Trials

Research on Optimal Immunization Strategy of Hepatitis B Vaccine in Chronic Kidney Disease Population

Start date: May 25, 2019
Phase: Phase 4
Study type: Interventional

At present, chronic kidney disease population are vaccinated with hepatitis B vaccine according to the standard three-dose schedule immunization program, and the effect of preventing HBV infection is not ideal. This is a randomized, controlled trial. The study will evaluate the immunogenicity and persistence of 20 µg and 60 µg recombinant hepatitis B vaccine with three or four injections at months 0, 1, and 6 or 0, 1, 2, and 6 in chronic kidney disease population.

NCT ID: NCT03962816 Not yet recruiting - Hepatitis B Vaccine Clinical Trials

Immunogenicity and Persistence of Hepatitis B Vaccination in Methadone Maintenance Treatment Patients

Start date: May 26, 2019
Phase: Phase 4
Study type: Interventional

At present, Methadone Maintenance Treatment Patients of Hepatitis B Vaccination in are vaccinated with hepatitis B vaccine according to the standard three-dose schedule immunization program, and the effect of preventing HBV infection is not ideal. This is a randomized, controlled trial. The study will evaluate the immunogenicity and persistence of 20 µg and 60 µg recombinant hepatitis B vaccine with three or four injections at months 0, 1, and 6 or 0, 1,2, and 6 in Methadone Maintenance Treatment Patients

NCT ID: NCT03962803 Not yet recruiting - Hepatitis B Vaccine Clinical Trials

Immunogenicity and Persistence of Hepatitis B Vaccination in HIV-Infected Patients

Start date: June 5, 2019
Phase: Phase 4
Study type: Interventional

At present, HIV-Infected Patients of Hepatitis B Vaccination in are vaccinated with hepatitis B vaccine according to the standard three-dose schedule immunization program, and the effect of preventing HBV infection is not ideal. This is a randomized, controlled trial. The study will evaluate the immunogenicity and persistence of 20 µg and 60 µg recombinant hepatitis B vaccine with three or four injections at months 0, 1, and 6 or 0, 1,2, and 6 in HIV-Infected Patients

NCT ID: NCT03733652 Not yet recruiting - Chronic Hepatitis b Clinical Trials

Optimal Treatment for Poor Efficacy of Entecavir in Chronic Hepatitis B Patients

Start date: November 15, 2018
Phase: N/A
Study type: Interventional

There are chronic hepatitis B patients with poor antiviral efficacy of entecavir in clinical practice. Tenofovir or interferon alfa is the optimal choice right now. The aim of this study is to investigate the therapeutic effect of using tenofovir of interferon alfa in these patients.

NCT ID: NCT03604016 Not yet recruiting - Hepatitis B Clinical Trials

Study to Assess Efficacy of Besifovir and L-carnitine in Chronic Hepatitis B Patients With Nonalcoholic Fatty Liver

Start date: September 23, 2018
Phase: Phase 4
Study type: Interventional

Pilot study to assess the antiviral activity and safety of Besifovir dipivoxil 150mg and L-carnitine 660mg compared to Tenofovir Alafenamide 25mg in chronic hepatitis B patients with Nonalcoholic fatty liver

NCT ID: NCT03566030 Not yet recruiting - Hepatitis B Clinical Trials

Switching From Tenofovir Disoproxi Fumarate to Tenofovir Alafenamide in Chronic Hepatitis B Patients With Antiviral Resistance

Start date: September 1, 2018
Phase:
Study type: Observational

- To evaluate the efficacy of switching to tenofovir alafenamide (TAF) 25 mg QD versus continued tenofovir disoproxil fumarate (TDF) 300 mg QD in CHB patients with antiviral resistance, as determined by the proportion of virologically suppressed patients at week 48 - To evaluate the safety and tolerability of switching to TAF 25 mg QD versus continuing TDF 300 mg QD in antiviral-resistant subjects with chronic HBV at week 48