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Clinical Trial Summary

As HBsAg clearance is uncommon in chronic hepatitis B (CHB) patients on nucleoside analogues (NAs) therapy. The purpose of this study is to optimize HBsAg clearance in CHB Patients with sequential treatment of pegylated interferon alpha-2b and NAs.


Clinical Trial Description

CHB Patients who had received, and responded to, NAs for more than 12 months are switched to receive peginterferon alfa-2b 80 micrograms/week for 48 weeks and follow up for 48 weeks. ;


Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02605252
Study type Interventional
Source Third Affiliated Hospital, Sun Yat-Sen University
Contact Xiang Zhu, Doctor
Phone +86-20-85252373
Email 0628zhuxiang@163.com
Status Recruiting
Phase N/A
Start date March 2016

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