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Hepatitis B, Chronic clinical trials

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NCT ID: NCT02327702 Not yet recruiting - Pregnancy Clinical Trials

Emtricitabine for Naive Chinese Pregnant Chronic Hepatitis B Patients

Start date: January 2015
Phase: Phase 4
Study type: Interventional

This study evaluates generic emtricitabine(FTC) efficacy and safety in Chinese naive pregnant chronic hepatitis B patients. Single group patients were enrolled to receive emtricitabine till 48 weeks after delivery.

NCT ID: NCT02327689 Not yet recruiting - Clinical trials for Hepatitis B, Chronic

Emtricitabine Plus Adefovir Dipivoxil for Naive Chinese HBV Related Cirrhosis Patients

Start date: January 2015
Phase: Phase 4
Study type: Interventional

This study evaluates generic emtricitabine(FTC) plus adefovir dipivoxil in Chinese naive HBV related cirrhosis patients. Patients were divided into 2 groups: compensated HBV related cirrhosis patients and decompensated HBV related cirrhosis patients.

NCT ID: NCT02327676 Not yet recruiting - Clinical trials for Hepatitis B, Chronic

Emtricitabine for Naive Child Chinese Chronic Hepatitis B Patients

Start date: January 2015
Phase: Phase 4
Study type: Interventional

This study evaluates generic emtricitabine(FTC) in Chinese naive children chronic hepatitis B patients. Single group of child patients were enrolled, which include HBeAg positive and negative Chronic hepatitis B(CHB)group.

NCT ID: NCT02327663 Not yet recruiting - Clinical trials for Hepatitis B, Chronic

Emtricitabine for Naive Chinese Chronic Hepatitis B Patients

Start date: December 2014
Phase: Phase 4
Study type: Interventional

This study evaluates generic emtricitabine(FTC) in Chinese naive chronic hepatitis B patients. Patients were divided into 2 groups: HBeAg positive Chronic hepatitis B(CHB)group and HBeAg negative Chronic hepatitis B(CHB)group.

NCT ID: NCT02056548 Not yet recruiting - Lymphoma Clinical Trials

Hepatitis B Virus Reactivation After Withdrawal of Preemptive Antiviral Therapy in Hematologic Malignancy

Start date: March 2014
Phase: N/A
Study type: Observational

Previous studies dealt with patients who maintained antiviral drugs for 2 ~ 6 months after final chemotherapy and they revealed that many of the patients who stopped preemptive antiviral drug within 6 months experienced viral reactivation. Based on the study results, guidelines recommend that preemptive antiviral therapy should be maintained for at least 6 months. Nevertheless, many clinicians apply the preemptive antiviral drugs for 1~2 years or longer after final chemotherapy without definite evidences, and this practice increases the medical expenditure a lot. Therefore, the investigators are going to find out the proper and safe duration of preemptive antiviral therapy which can be a good reference in the future practice.

NCT ID: NCT01776814 Not yet recruiting - Chronic Hepatitis B Clinical Trials

Comparison of the Efficacy of Entecavir and Tenofovir Monotherapy for the Treatment of Nucleos(t)Ide-naïve Patients With Chronic Hepatitis B in Korea

Start date: February 2013
Phase: N/A
Study type: Observational

Chronic hepatitis B virus infection is an important cause of morbidity and mortality. Tenofovir disoproxil fumarate and entecavir were licensed for the treatment of hepatitis B virus infection. In this study, the investigators will try to make comparison between Entecavir and Tenofovir and investigate the efficacy.

NCT ID: NCT01436539 Not yet recruiting - Chronic Hepatitis B Clinical Trials

Study of Effects and Safety Between Adefovir Dipivoxil Plus Polyene Phosphatidylcholine Versus Adefovir Dipivoxil Alone in Chronic Hepatitis B Patients

Start date: September 2011
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate the effects and safety of Adefovir Dipivoxil plus polyene phosphatidylcholine compared to Adefovir Dipivoxil alone in patients with chronic hepatitis B.

NCT ID: NCT01270178 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Entecavir for Chronic Hepatitis B in Hepatocellular Carcinoma Patients Underwent Radiofrequency Ablation Therapy

Start date: January 2011
Phase: N/A
Study type: Observational

Persistent replication of HBV (47-55%) is frequently found in patients with HCC, which in turn leads to deterioration of liver reserve. Moreover, a large proportion of HCC patients who underwent curative therapy died from progressive liver decompensation rather than recurrence of cancer. It had been proved that anti-viral therapy for hepatitis C virus (HCV)-related HCC patients could reduce the rate of tumor recurrence after surgical resection. This is a prospective study to evaluate the efficacy of ETV therapy in chronic hepatitis B patients after receiving RFA therapy for HCC.

NCT ID: NCT00815464 Not yet recruiting - Liver Diseases Clinical Trials

A Single-Arm Study Evaluating the Efficacy of Liquid Acupuncture Therapeutics in Chronic Hepatitis B

CHB
Start date: March 2009
Phase: N/A
Study type: Interventional

Study Purpose: The purpose of this study is to assess that Liquid Acupuncture(Herb Acupoints Injection) Therapeutics could achieve permanent efficacy response in Chronic Hepatitis B. Efficacy Assessment: At cessation of the Treatment(about at 24 weeks)comparing Testing Data with the Normal Criteria and their individual baseline.Continue for monitoring the Status 1-5 years. Data Analysis: Each 4 weeks collecting Patients' testing data and fill a table.A summary table will be presented as frequency tables for categorical variables as number or percentage.

NCT ID: NCT00753467 Not yet recruiting - Hepatitis B Clinical Trials

A Phase II Study to Determine the Safety and Efficacy of Interferon-gamma in Patients With Chronic Hepatitis B

Start date: September 2008
Phase: Phase 2
Study type: Interventional

Open-label, prospective, two part study evaluating IFN-γ 1b at a dose of 200μg by subcutaneous injection every day either alone or in combination with Adefovir dipivoxil or Adefovir dipivoxil alone at a dose of 10mg QD in patients with chronic Hepatitis B.