Hepatitis, Autoimmune Clinical Trial
Official title:
Evaluation of the Cellular Immune Response in Patients With Anti-SLA/LP- or Anti-LKM-Positive Autoimmune Hepatitis
The purpose of the study is to determine the role special antibodies play in possibly
identifying Autoimmune Hepatitis through the following:
Identify the response of specific T cells to antibodies and Monitor the response of the
cells that regulate the immune system
The object of this protocol is to characterize and monitor auto antigen-specific T cell responses in blood and liver biopsies of patients with anti-SLA/LP or anti-LKM-positive autoimmune hepatitis. The results will provide insight into the pathogenesis of autoimmune hepatitis and the monitoring of auto antigen-specific T cell reactivity in correlation to disease exacerbation and therapy. ;
Time Perspective: Prospective
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