Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study — Treatment IND

Hepatic Veno-Occlusive Disease Clinical Trial

Official title:
Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study

Status Completed

Clinical Trial Summary

Single arm, open-label study to provide Defibrotide to patients diagnosed with VOD. Defibrotide is no longer available though the Emergency Use IND mechanism (also known as compassionate use, or single patient named use). This protocol is the only mechanism by which Defibrotide can be made available to patients in the U.S.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Hepatic Veno-Occlusive Disease

Clinical Trial Details

NCT number	NCT00628498
Study type	Interventional
Source	Jazz Pharmaceuticals
Contact
Status	Completed
Phase	Phase 3
Start date	December 2007
Completion date	September 2016

View Details

See also
Status	Clinical Trial	Phase
No longer available	`NCT00143546` - Compassionate Use of Defibrotide for Patients With Veno-occlusive Disease of the Liver	N/A
Active, not recruiting	`NCT01886248` - Antithrombin-III for Patients With Hepatic Veno-occlusive Diseases Following Hematopoietic Stem Cell Transplantation	Phase 2
Recruiting	`NCT00563498` - Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients	N/A
Not yet recruiting	`NCT04168788` - Pharmacogenetic Study of Antimitotic Therapies Involved in Hepatic VOD in Children With Nephroblastoma or ALL	N/A
Completed	`NCT00272948` - Pediatric Trial Investigating the Incidence & Outcome of Veno-Occlusive Disease With the Prophylactic Use of Defibrotide	Phase 2/Phase 3
Completed	`NCT03032016` - European VOD Registry