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Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

Hepatic Encephalopathy Clinical Trial

Official title:
Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

Clinical Trial Summary

Readmission rates for patients with hepatic encephalopathy due to end stage liver disease are high. Hyperammonemia contributes significantly to encephalopathy and occurs because of impaired hepatic ureagenesis and increased skeletal muscle proteolysis. We propose a randomized, 6-month nutritional intervention in cirrhotic patients who have had at least 1 admission for hepatic encephalopathy within the last 6 months. We hypothesize that a combination of late evening and early morning protein supplement (Ensure Enlive) will decrease recurrent hepatic encephalopathy and consequent readmission rates by lowering skeletal muscle proteolysis and improved lean body mass.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04096014
Study type Interventional
Source The Cleveland Clinic
Contact Annette C Bellar
Phone 2166365247
Email bellara@ccf.org
Status Recruiting
Phase N/A
Start date September 16, 2019
Completion date October 30, 2026
View Details
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