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Fecal Microbiota Transplantation (FMT) in the Management of Hepatic Encephalopathy (HE): a Pilot Study

Hepatic Encephalopathy Clinical Trial

Official title:
A Prospective, Single Center, Open Label Trial of Fecal Microbiota Transplantation (FMT) in the Management of Hepatic Encephalopathy (HE): a Pilot Study

Clinical Trial Summary

The purpose of this study is to determine if FMT can reverse Hepatic Encephlopathy (HE) in cirrhotic patients who continue to have breakthrough episodes of HE despite maintenance therapy with lactulose and/or rifaximin or metronidazole.

Clinical Trial Description

Subjects receive FMT from a single donor by colonoscopy at Week 0 and by enema at Weeks 1-4. HE is measured by Inhibitory Control Test and Stroop as well as serum ammonia levels. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02255617
Study type Interventional
Source University of Alberta
Contact
Status Completed
Phase Phase 1/Phase 2
Start date July 23, 2014
Completion date September 23, 2019
View Details
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