Thrombosis Clinical Trial
Official title:
Thrombotic Biomarkers to Predict Thrombosis in Heparin-induced Thrombocytopenia
Heparin induced thrombocytopenia (HIT) is a kind of catastrophic thrombotic complications
after the application of heparin. If HIT without treatment, death rate is as high as 30% to
50%. Early diagnosis of HIT and prevention of thrombosis is very important.
This study is planned to assess the use of thrombotic biomarkers in patients with HIT,
including thrombin-antithrombin complex, d-dimer, fibrin degradation products and
Thrombelastograghy monitoring . These biomarkers are monitored in 5-14 days post-operation to
assess the risk of thrombosis in HIT patients. All patients were followed up for 30 days, and
clinical outcomes, including new thrombus and death, were recorded during follow-up.
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